Pathogenic variants damage cell composition and single cell transcription in cardiomyopathies
D Reichart, EL Lindberg, H Maatz, AMA Miranda… - Science, 2022 - science.org
Pathogenic variants in genes that cause dilated cardiomyopathy (DCM) and arrhythmogenic
cardiomyopathy (ACM) convey high risks for the development of heart failure through …
cardiomyopathy (ACM) convey high risks for the development of heart failure through …
Vulnerable atherosclerotic plaque: is there a molecular signature?
Atherosclerosis and its clinical manifestations, coronary and cerebral artery diseases, are
the most common cause of death worldwide. The main pathophysiological mechanism for …
the most common cause of death worldwide. The main pathophysiological mechanism for …
Single-cell RNA sequencing in vision research: Insights into human retinal health and disease
Gene expression provides valuable insight into cell function. As such, vision researchers
have frequently employed gene expression studies to better understand retinal physiology …
have frequently employed gene expression studies to better understand retinal physiology …
RGCC balances self‐renewal and neuronal differentiation of neural stem cells in the developing mammalian neocortex
Z Guo, M Chen, Y Chao, C Cai, L Liu, L Zhao, L Li… - EMBO …, 2021 - embopress.org
During neocortical development, neural stem cells (NSCs) divide symmetrically to self‐
renew at the early stage and then divide asymmetrically to generate post‐mitotic neurons …
renew at the early stage and then divide asymmetrically to generate post‐mitotic neurons …
Diclofenac Disrupts the Circadian Clock and through Complex Cross-Talks Aggravates Immune-Mediated Liver Injury—A Repeated Dose Study in Minipigs for 28 …
S Selvaraj, JH Oh, S Yoon, J Borlak - International Journal of Molecular …, 2023 - mdpi.com
Diclofenac effectively reduces pain and inflammation; however, its use is associated with
hepato-and nephrotoxicity. To delineate mechanisms of injury, we investigated a clinically …
hepato-and nephrotoxicity. To delineate mechanisms of injury, we investigated a clinically …
Autoantibodies against cytoskeletons and lysosomal trafficking discriminate sarcoidosis from healthy controls, tuberculosis and lung cancers
SN Hanoudi, H Talwar, S Draghici, L Samavati - Molecular Biomedicine, 2022 - Springer
Sarcoidosis is a systemic granulomatous disease of unknown etiology.
Hypergammaglobulinemia and the presence of autoantibodies in sarcoidosis suggest active …
Hypergammaglobulinemia and the presence of autoantibodies in sarcoidosis suggest active …
Oncogenic gene RGC‐32 is a direct target of miR‐26b and facilitates tongue squamous cell carcinoma aggressiveness through EMT and PI3K/AKT signalling
ZH Yang, J Li, WZ Chen… - Cell Biochemistry and …, 2020 - Wiley Online Library
Growing data have recognized the significance of Response Gene to Complement (RGC)‐
32 in numerous tumour developments. Notwithstanding, the functional role and underlying …
32 in numerous tumour developments. Notwithstanding, the functional role and underlying …
Single-Cell RNA-Sequencing Analyses Identify APLNR, INS-IGF2, RGCC Genes May Be Involved in the Pathogenesis of Systemic Sclerosis Skin
P Zhu, W Deng - Clinical, Cosmetic and Investigational …, 2024 - Taylor & Francis
Background Systemic sclerosis represents a persistent autoimmune disorder marked with
fibrosis affecting both skin and other organs, which leads to a diminished quality of life and …
fibrosis affecting both skin and other organs, which leads to a diminished quality of life and …
Molecular analyses of the human retina and choroid at the single cell level
AP Voigt - 2023 - search.proquest.com
Age-related macular degeneration (AMD) is a common cause of irreversible blindness
globally. The disease results in loss of light-sensing photoreceptor cells in the center of the …
globally. The disease results in loss of light-sensing photoreceptor cells in the center of the …
RGCC is a Prognostic Biomarker and Correlates with Immune Infiltrates in Breast Cancer
H Zhang, Y Su, J Jia, Q Wang - 2023 - researchsquare.com
Background RGCC (regulator of cell cycle) is a protein-coding gene, also known as RGC-32
(response gene to complement 32 protein), which is an important regulatory gene of cell …
(response gene to complement 32 protein), which is an important regulatory gene of cell …