[HTML][HTML] Natural products targeting Nrf2/ARE signaling pathway in the treatment of inflammatory bowel disease

B Li, Y Wang, X Jiang, H Du, Y Shi, M Xiu, Y Liu… - Biomedicine & …, 2023 - Elsevier
Inflammatory bowel disease (IBD) is a special chronic intestinal inflammatory disease, which
is mainly divided into Crohn's disease (CD) and ulcerative colitis (UC). Its occurrence is a …

Genistein-derived ROS-responsive nanoparticles relieve colitis by regulating mucosal homeostasis

W Fan, S Zhang, Y Wu, T Lu, J Liu, X Cao… - … Applied Materials & …, 2021 - ACS Publications
Disruption of intestinal homeostasis is an important event in the development of
inflammatory bowel disease (IBD), and genistein (GEN) is a candidate medicine to prevent …

The potential of natural oils to improve inflammatory bowel disease

Y Zhou, D Wang, H Duan, S Zhou, J Guo, W Yan - Nutrients, 2023 - mdpi.com
Inflammatory bowel disease (IBD) is a chronic intestinal inflammatory disorder that includes
ulcerative colitis (UC) and Crohn's disease (CD), the exact cause of which is still unknown …

Therapeutic effects of genistein in experimentally induced ulcerative colitis in rats via affecting mitochondrial biogenesis

TS Alharbi, ZS Alshammari, ZN Alanzi… - Molecular and Cellular …, 2024 - Springer
Ulcerative colitis (UC) is an inflammatory bowel disease that affects the mucosa of the colon,
resulting in severe inflammation and ulcers. Genistein is a polyphenolic isoflavone present …

Anti‐Inflammatory, Antioxidant, and Healing‐Promoting Effects of Aloe vera Extract in the Experimental Colitis in Rats

MA Naini, A Zargari-Samadnejad… - Evidence‐Based …, 2021 - Wiley Online Library
Background. Ulcerative colitis is a worldwide chronic gastrointestinal disease characterized
by variable extensions of colon mucosal inflammation. The available drugs have an …

Genistein and/or sulfasalazine ameliorate acetic acid-induced ulcerative colitis in rats via modulating INF-γ/JAK1/STAT1/IRF-1, TLR-4/NF-κB/IL-6, and JAK2/STAT3 …

EA Elhefnawy, HF Zaki, NN El Maraghy… - Biochemical …, 2023 - Elsevier
Ulcerative Colitis (UC) is a chronic idiopathic inflammatory bowel disease in which the
colon's lining becomes inflamed. Exploring herbal remedies that can recover mucosal …

Genistein microparticles prepared by antisolvent recrystallization with low-speed homogenization process

X Zhang, Y Huang, H Zhu, Z Liu, L Zhang, Z Li, Y Niu… - Food Chemistry, 2023 - Elsevier
To create genistein particles, a brand-new antisolvent recrystallization technique was
employed. The response surface approach was utilized to optimize the single factor test …

Genistein Inhibits Colonic Goblet Cell Loss and Colorectal Inflammation Induced by Salmonella Typhimurium Infection

Y He, H Ayansola, Q Hou, C Liao, J Lei… - Molecular Nutrition & …, 2021 - Wiley Online Library
Scope Salmonella is the main food‐borne pathogen, which can infect intestinal epithelial
cells and causes colitis. Genistein has a variety of biological activities that alleviates colitis …

The Antioxidant and Anti‐Inflammatory Effects of Quercus brantii Extract on TNBS‐Induced Ulcerative Colitis in Rats

M Alizade Naini, S Mehrvarzi… - Evidence‐Based …, 2021 - Wiley Online Library
Objectives. Ulcerative colitis is a common subtype of persistent inflammatory bowel disease
with high morbidity consequences. Despite unknown definite pathogenesis, multiple anti …

Effect of flaxseed oil on biochemical parameters, hormonal indexes and stereological changes in ovariectomized rats

R Tanideh, S Delavari, O Farshad… - Veterinary Medicine …, 2021 - Wiley Online Library
The ovariectomized rat is a widely used preclinical model for studying postmenopausal and
its complications. In this study, the therapeutic effect of flaxseed oil on the ovariectomized …