The vascular endothelial growth factor family in adverse pregnancy outcomes

PH Andraweera, GA Dekker… - Human reproduction …, 2012 - academic.oup.com
BACKGROUND Pre-eclampsia, small-for-gestational-age infants, preterm birth and
recurrent miscarriage complicate a significant number of pregnancies. The vascular …

Medically indicated preterm birth: recognizing the importance of the problem

CV Ananth, AM Vintzileos - Clinics in perinatology, 2008 - Elsevier
Preterm birth complicates over 500,000 births annually, affecting 12.5% of pregnancies in
the United States. Much of the temporal increase in preterm birth (< 37 weeks) over the past …

Stereological investigation of placental morphology in pregnancies complicated by pre-eclampsia with and without intrauterine growth restriction

TM Mayhew, C Ohadike, PN Baker, IP Crocker… - Placenta, 2003 - Elsevier
The aim of this study was to quantify placental morphology in pregnancies complicated by
pre-eclampsia with and without intrauterine growth restriction. Particular attention is given to …

Urinary angiogenic factors cluster hypertensive disorders and identify women with severe preeclampsia

CS Buhimschi, ER Norwitz, E Funai, S Richman… - American journal of …, 2005 - Elsevier
OBJECTIVE: Serum levels of soluble fms-like tyrosine kinase 1 (sFlt-1), vascular endothelial
growth factor (VEGF), and placental growth factor (PlGF) are altered in women with clinical …

Vascular endothelial growth factor gene polymorphisms and pre‐eclampsia

D Papazoglou, G Galazios… - MHR: Basic science …, 2004 - academic.oup.com
Vascular endothelial growth factor (VEGF) plays a crucial role in physiological
vasculogenesis and vascular permeability and has been implicated in the pathogenesis of …

Placental growth factor, vascular endothelial growth factor, and hypoxia-inducible factor-1α in the placentas of women with pre-eclampsia

LE Ali, MM Salih, EM Elhassan… - The Journal of …, 2019 - Taylor & Francis
Background: Although the exact mechanism of pre-eclampsia–high blood pressure and
proteinuria after 20 gestational weeks–is not yet fully understood, placental growth factor …

VEGF expression in the placenta from pregnancies complicated by hypertensive disorders

E Sgambati, M Marini… - … Journal of Obstetrics …, 2004 - Wiley Online Library
Objective To determine the expression of VEGF in the placental tissue from pregnancies
complicated by hypertension disorders of different clinical severity. Design Prospective …

Hypoxia activates the human placental vascular endothelial growth factor system in vitro and in vivo: up-regulation of vascular endothelial growth factor in clinically …

R Trollmann, K Amann, E Schoof, E Beinder… - American journal of …, 2003 - Elsevier
Objective: We investigated the influence of acute hypoxia on the placental vascular
endothelial growth factor system in vitro and in vivo in acute birth asphyxia compared with …

Regional anesthesia in patients with pregnancy induced hypertension

SP Ankichetty, KJ Chin, VW Chan… - Journal of …, 2013 - journals.lww.com
Pregnancy induced hypertension is a hypertensive disorder, which occurs in 5% to 7% of all
pregnancies. These parturients present to the labour and delivery unit ranging from …

The pathophysiology of preeclampsia involves altered levels of angiogenic factors promoted by hypoxia and autoantibody-mediated mechanisms

E Laresgoiti-Servitje, N Gomez-Lopez - Biology of reproduction, 2012 - academic.oup.com
Pre-eclampsia is a syndrome characterized by inadequate placentation, which is due to
deficient trophoblastic invasion of the uterine spiral arteries. This deficiency can lead to …