Inorganic nanoparticles as scaffolds for bioorthogonal catalysts

CM Hirschbiegel, X Zhang, R Huang, YA Cicek… - Advanced drug delivery …, 2023 - Elsevier
Bioorthogonal transition metal catalysts (TMCs) transform therapeutically inactive molecules
(pro-drugs) into active drug compounds. Inorganic nanoscaffolds protect and solubilize …

Target‐Specific Bioorthogonal Reactions for Precise Biomedical Applications

Z Liu, M Sun, W Zhang, J Ren, X Qu - Angewandte Chemie, 2023 - Wiley Online Library
Bioorthogonal chemistry is a promising toolbox for dissecting biological processes in the
native environment. Recently, bioorthogonal reactions have attracted considerable attention …

Boosting Endogenous Copper (I) for Biologically Safe and Efficient Bioorthogonal Catalysis via Self-Adaptive Metal–Organic Frameworks

J Zhu, Y You, W Zhang, F Pu, J Ren… - Journal of the American …, 2023 - ACS Publications
As one of the most typical bioorthogonal reactions, the Cu (I)-catalyzed azide–alkyne 1, 3-
cycloaddition (CuAAC) reaction has received worldwide attention in intracellular …

Nanozyme-based remodeling of disease microenvironments for disease prevention and treatment: a review

Y Ju, X Liu, X Ye, M Dai, B Fang… - ACS Applied Nano …, 2023 - ACS Publications
Nanomaterials that can mimic the activity of various enzymes have been studied extensively
in the biomedical field in recent years. Nanozymes offer better stability and economic value …

Harnessing transition metal scaffolds for targeted antibacterial therapy

C Weng, YLK Tan, WG Koh… - Angewandte Chemie …, 2023 - Wiley Online Library
Antimicrobial resistance, caused by persistent adaptation and growing resistance of
pathogenic bacteria to overprescribed antibiotics, poses one of the most serious and urgent …

Bioorthogonal nanozymes for breast cancer imaging and therapy

X Zhang, Y Liu, J Doungchawee… - Journal of Controlled …, 2023 - Elsevier
Bioorthogonal catalysis via transition metal catalysts (TMCs) enables the generation of
therapeutics locally through chemical reactions not accessible by biological systems. This …

Nanotechnology reinforced neutrophil-based therapeutic strategies for inflammatory diseases therapy

J Wu, T Ma, M Zhu, T Huang, B Zhang, J Gao, N Lin - Nano Today, 2022 - Elsevier
Misguided attack of immune systems on self-tissue or multifactorial uncontrolled
inflammation is capable of causing inflammatory diseases. Neutrophils play a critical role in …

Pathogen‐Targeting Bimetallic Nanozymes as Ultrasonic‐Augmented ROS Generator against Multidrug Resistant Bacterial Infection

H Yao, R Zhou, J Wang, Y Wei, S Li… - Advanced …, 2023 - Wiley Online Library
Clinical treatment of multidrug resistant (MDR) pathogens‐induced infection is emerging as
a growing challenge in global public health due to the limited selection of clinically available …

Red blood cell inspired strategies for drug delivery: emerging concepts and new advances

E Zhang, P Phan, HA Algarni, Z Zhao - Pharmaceutical Research, 2022 - Springer
In the past five decades, red blood cells (RBCs) have been extensively explored as drug
delivery systems due to their distinguishing potential in modulating the pharmacokinetic …

Red blood cells: a potential delivery system

M Chen, Y Leng, C He, X Li, L Zhao, Y Qu… - Journal of …, 2023 - Springer
Red blood cells (RBCs) are the most abundant cells in the body, possessing unique
biological and physical properties. RBCs have demonstrated outstanding potential as …