Insulin resistance (IR) plays a crucial role in the development and progression of
metabolism-related diseases such as diabetes, hypertension, tumors, and nonalcoholic fatty …

Randomised trials reported up to Dec 31, 2012, did not confirm that vitamin D
supplementation could protect from non-skeletal health conditions affecting adults, as was …

Background Observational studies support an association between a low blood 25-
hydroxyvitamin D level and the risk of type 2 diabetes. However, whether vitamin D …

Background A large number of observational studies have reported harmful effects of low 25-
hydroxyvitamin D (25OHD) levels on non-skeletal outcomes. We performed a systematic …

BACKGROUND While observational studies have shown an association between vitamin D
insufficiency and diabetes, it is unclear whether intervention with vitamin D supplements can …

Vitamin D deficiency could play an important role in the pathogenesis of type 2 diabetes
mellitus (T2DM) as it may alter several crucial processes in the development of diabetes and …

Vitamin D is a precursor of the steroid hormone calcitriol that is crucial for bone and mineral
metabolism. Both the high prevalence of vitamin D deficiency in the general population and …

Vitamin D deficiency is associated with a decreased insulin release, insulin resistance and
type 2 diabetes in experimental and epidemiological studies. Animal studies show that 1α …

PTH and Vitamin D are two major regulators of mineral metabolism. They play critical roles
in the maintenance of calcium and phosphate homeostasis as well as the development and …

Vitamin D deficiency is typically caused by inadequate cutaneous synthesis secondary to
decreased exposure to sunlight. Serum levels of 25-hydroxyvitamin D l< 20 ng/ml are …