Most patients diagnosed with head and neck squamous cell carcinoma (HNSCC) will
present with locally advanced disease, requiring multimodality therapy. While this approach …

Answer questions and earn CME/CNE Human papillomavirus (HPV), one of the most
common sexually transmitted diseases worldwide, has an established role in the …

Purpose To report the long-term results of the Intergroup Radiation Therapy Oncology Group
91-11 study evaluating the contribution of chemotherapy added to radiation therapy (RT) for …

Glioblastoma (GBM) is the most common and lethal type of malignant brain tumor in adults.
Currently, interventions are lacking, the median overall survival of patients with GBM is less …

As a type of programmed cell death, ferroptosis is distinct from apoptosis. The combination
of the two thus provides a promising modality with which to significantly improve anticancer …

Purpose To evaluate induction chemotherapy with docetaxel, cisplatin, and fluorouracil
(TPF) followed by surgery and postoperative radiotherapy versus up-front surgery and …

Platinum based drugs alone or in combination with 5FU and docetaxel are common regimen
chemotherapeutics for the treatment of advanced OSCC. Chemoresistance is one of the …

Purpose Cisplatin plus fluorouracil (PF) induction chemotherapy has been compared with
taxane (docetaxel or paclitaxel), cisplatin, and fluorouracil (Tax-PF) in randomized trials in …

Background Randomised, controlled trials and meta-analyses have shown the survival
benefit of concomitant chemoradiotherapy or hyperfractionated radiotherapy in the treatment …

The past several years have seen major advances in the use of systemic therapy for
treatment of patients with oral cancer. Systemic therapy refers to chemotherapy and …