Natural polymer‐derived bioscaffolds for peripheral nerve regeneration

H Zhang, J Guo, Y Wang, L Shang… - Advanced Functional …, 2022 - Wiley Online Library
In recent decades, artificial nerve scaffolds have become a promising substitute for
peripheral nerve repair. Considerable efforts have been devoted to improving the …

Neuro–bone tissue engineering: emerging mechanisms, potential strategies, and current challenges

W Sun, B Ye, S Chen, L Zeng, H Lu, Y Wan, Q Gao… - Bone Research, 2023 - nature.com
The skeleton is a highly innervated organ in which nerve fibers interact with various skeletal
cells. Peripheral nerve endings release neurogenic factors and sense skeletal signals …

3D printed conductive multiscale nerve guidance conduit with hierarchical fibers for peripheral nerve regeneration

Y Fang, C Wang, Z Liu, J Ko, L Chen… - Advanced …, 2023 - Wiley Online Library
Nerve guidance conduits (NGCs) have become a promising alternative for peripheral nerve
regeneration; however, the outcome of nerve regeneration and functional recovery is greatly …

Biomimetic asymmetric composite dressing by electrospinning with aligned nanofibrous and micropatterned structures for severe burn wound healing

C He, B Yu, Y Lv, Y Huang, J Guo, L Li… - … Applied Materials & …, 2022 - ACS Publications
The surface structure and topography of biomaterials play a crucial role in directing cell
behaviors and fates. Meanwhile, asymmetric dressings that mimic the natural skin structure …

Aligned electrospun poly(l-lactide) nanofibers facilitate wound healing by inhibiting macrophage M1 polarization via the JAK-STAT and NF-κB pathways

J Xie, X Wu, S Zheng, K Lin, J Su - Journal of nanobiotechnology, 2022 - Springer
Delayed wound healing remains a challenge, and macrophages play an important role in
the inflammatory process of wound healing. Morphological changes in macrophages can …

[HTML][HTML] Advancing neural regeneration via adaptable hydrogels: Enriched with Mg2+ and silk fibroin to facilitate endogenous cell infiltration and macrophage …

Y Gao, Y Wang, J Zhang, M Zhang, C Dai, Y Zhang… - Bioactive Materials, 2024 - Elsevier
Peripheral nerve injury is a complex and challenging medical condition due to the limited
ability of nerves to regenerate, resulting in the loss of both sensory and motor function …

Oriented nanofibrous P (MMD-co-LA)/Deferoxamine nerve scaffold facilitates peripheral nerve regeneration by regulating macrophage phenotype and …

X Dong, P Wu, L Yan, K Liu, W Wei, Q Cheng, X Liang… - Biomaterials, 2022 - Elsevier
Delayed injured nerve regeneration remains a clinical problem, partly ascribing to the lack of
regulation of regenerative microenvironment, topographical cues, and blood nourishment …

An injectable and adaptable hydrogen sulfide delivery system for modulating neuroregenerative microenvironment

X Dong, H Zhang, P Duan, K Liu, Y Yu, W Wei… - Science …, 2023 - science.org
Peripheral nerve regeneration is a complex physiological process. Single-function nerve
scaffolds often struggle to quickly adapt to the imbalanced regenerative microenvironment …

[HTML][HTML] Biomechanical microenvironment in peripheral nerve regeneration: from pathophysiological understanding to tissue engineering development

L Kong, X Gao, Y Qian, W Sun, Z You, C Fan - Theranostics, 2022 - ncbi.nlm.nih.gov
Peripheral nerve injury (PNI) caused by trauma, chronic disease and other factors may lead
to partial or complete loss of sensory, motor and autonomic functions, as well as neuropathic …

[HTML][HTML] Micro-nanofiber composite biomimetic conduits promote long-gap peripheral nerve regeneration in canine models

X Dong, Y Yang, Z Bao, AC Midgley, F Li, S Dai… - Bioactive Materials, 2023 - Elsevier
Peripheral nerve injuries may result in severe long-gap interruptions that are challenging to
repair. Autografting is the gold standard surgical approach for repairing long-gap nerve …