Synthesis and medical applications of oligosaccharides

PH Seeberger, DB Werz - Nature, 2007 - nature.com
Our understanding of the different glycoconjugates present on cells, proteins and entire
organisms is lagging far behind advances in genomics and proteomics. Carbohydrate …

Carbohydrate microarrays

S Park, JC Gildersleeve, O Blixt, I Shin - Chemical Society Reviews, 2013 - pubs.rsc.org
In the last decade, carbohydrate microarrays have been core technologies for analyzing
carbohydrate-mediated recognition events in a high-throughput fashion. A number of …

Glycan arrays: recent advances and future challenges

O Oyelaran, JC Gildersleeve - Current opinion in chemical biology, 2009 - Elsevier
Carbohydrate arrays, also referred to as glycan arrays, are composed of various
oligosaccharides and/or polysaccharides immobilized on a solid support in a spatially …

Carbohydrate microarrays: key developments in glycobiology

Y Liu, AS Palma, T Feizi - 2009 - degruyter.com
Carbohydrate chains of glycoproteins, glycolipids, proteoglycans, and polysaccharides
mediate processes of biological and medical importance through their interactions with …

Glycan arrays: biological and medical applications

PH Liang, CY Wu, WA Greenberg, CH Wong - Current opinion in chemical …, 2008 - Elsevier
Carbohydrates and their conjugates are involved in various biological events, including viral
and bacterial infection, the immune response, differentiation and development, and the …

Glycan arrays: from basic biochemical research to bioanalytical and biomedical applications

A Geissner, PH Seeberger - Annual Review of Analytical …, 2016 - annualreviews.org
A major branch of glycobiology and glycan-focused biomedicine studies the interaction
between carbohydrates and other biopolymers, most importantly, glycan-binding proteins …

Lectinomics: II. A highway to biomedical/clinical diagnostics

P Gemeiner, D Mislovičová, J Tkáč, J Švitel… - Biotechnology …, 2009 - Elsevier
The review assesses current status and attempts to forecast trends in the development of
lectin biorecognition technology. The progressive trend is characterized scientometrically …

Glycan and lectin microarrays for glycomics and medicinal applications

J Katrlík, J Švitel, P Gemeiner, T Kožár… - Medicinal research …, 2010 - Wiley Online Library
Three different array formats to study a challenging field of glycomics are presented here,
based on the use of a panel of immobilized glycan or lectins, and on in silico computational …

[PDF][PDF] On‐chip synthesis and label‐free assays of oligosaccharide arrays

L Ban, M Mrksich - Angewandte Chemie, 2008 - academia.edu
Oligosaccharides, like proteins and DNA, are ubiquitous biopolymers that mediate essential
functions in organisms.[1] Yet, an understanding of the many roles that carbohydrates play is …

Surface plasmon resonance imaging for real-time, label-free analysis of protein interactions with carbohydrate microarrays

R Karamanska, J Clarke, O Blixt, JI MacRae… - Glycoconjugate …, 2008 - Springer
Plant lectin recognition of glycans was evaluated by SPR imaging using a model array of N-
biotinylated aminoethyl glycosides of β-d-glucose (negative control), α-d-mannose (conA …