The role of microRNAs in the pathophysiology of human central nervous system: a focus on neurodegenerative diseases
Abstract microRNAs (miRNAs) are suggested to play substantial roles in regulating the
development and various physiologic functions of the central nervous system (CNS). These …
development and various physiologic functions of the central nervous system (CNS). These …
Noncoding RNAs in extracellular fluids as cancer biomarkers: the new frontier of liquid biopsies
The last two decades of cancer research have been devoted in two directions:(1)
understanding the mechanism of carcinogenesis for an effective treatment, and (2) …
understanding the mechanism of carcinogenesis for an effective treatment, and (2) …
Recent trends in miRNA therapeutics and the application of plant miRNA for prevention and treatment of human diseases
Background Researchers now have a new avenue to investigate when it comes to miRNA-
based therapeutics. miRNAs have the potential to be valuable biomarkers for disease …
based therapeutics. miRNAs have the potential to be valuable biomarkers for disease …
MicroRNA as a potential therapeutic molecule in cancer
Small noncoding RNAs, as post-translational regulators of many target genes, are not only
markers of neoplastic disease initiation and progression, but also markers of response to …
markers of neoplastic disease initiation and progression, but also markers of response to …
[HTML][HTML] Crosstalk among NLRP3 inflammasome, ETBR signaling, and miRNAs in stress-induced depression-like behavior: a modulatory role for SGLT2 inhibitors
Depression is an overwhelming health concern, and many patients fail to optimally respond
to available standard therapies. Neuroplasticity and blood–brain barrier (BBB) integrity are …
to available standard therapies. Neuroplasticity and blood–brain barrier (BBB) integrity are …
Targeted delivery of miRNA based therapeuticals in the clinical management of Glioblastoma Multiforme
Glioblastoma multiforme (GBM) is the most aggressive (WHO grade IV) form of diffuse
glioma endowed with tremendous invasive capacity. The availability of narrow therapeutic …
glioma endowed with tremendous invasive capacity. The availability of narrow therapeutic …
MicroRNAs in central nervous system diseases: a prospective role in regulating blood-brain barrier integrity
Given the essential role of the blood-brain barrier (BBB) in the central nervous system
(CNS), cumulative investigations have been performed to elucidate how modulation of BBB …
(CNS), cumulative investigations have been performed to elucidate how modulation of BBB …
The role of non-coding RNAs in glioma
For decades, research in cancer biology has been focused on the protein-coding fraction of
the human genome. However, with the discovery of non-coding RNAs (ncRNAs), it has …
the human genome. However, with the discovery of non-coding RNAs (ncRNAs), it has …
[HTML][HTML] Clinical application of intrathecal gadobutrol for assessment of cerebrospinal fluid tracer clearance to blood
PK Eide, E Mariussen, H Uggerud, AH Pripp… - JCI insight, 2021 - ncbi.nlm.nih.gov
BACKGROUND Methodology for estimation of cerebrospinal fluid (CSF) tracer clearance
could have wide clinical application in predicting excretion of intrathecal drugs and …
could have wide clinical application in predicting excretion of intrathecal drugs and …
miRNA involvement in cerebral ischemia-reperfusion injury
Cerebral ischemia reperfusion injury is a debilitating medical condition, currently with only a
limited amount of therapies aimed at protecting the cerebral parenchyma. Micro RNAs …
limited amount of therapies aimed at protecting the cerebral parenchyma. Micro RNAs …