Simple Summary Lynch syndrome (LS) stands as the predominant inherited cancer
condition at present. Currently, surveillance is based on genotype-driven strategies and …

Summary Background Individuals with Lynch syndrome are at high risk for colorectal cancer
(CRC). Regular colonoscopies have proven to decrease CRC incidence and mortality …

METHODS: We searched the provincial pathology database with “adenocarcinoma” in the
colorectal specimen pathology reports between March 2018 and December 2020. We cross …

Lynch syndrome (LS), also known as hereditary nonpolyposis colorectal cancer (HNPCC), is
a disorder caused by an autosomal dominant heterozygous germline mutation in one of the …

The clinical value of population-based genetic screening projects depends on the actions
taken on the findings. The Healthy Nevada Project (HNP) is an all-comer genetic screening …

Background Non‐invasive biomarkers may reduce post‐colonoscopy colorectal cancer
(CRC) rates and colonoscopy overuse in Lynch syndrome. Unlike faecal immunochemical …

Background Persons suspected or confirmed with familial colorectal cancer syndrome are
recommended to have biennial colonoscopy from late adolescence or early adulthood …

Objectives: Colonoscopy surveillance for Lynch syndrome is burdensome and post-
colonoscopy colorectal cancers (CRCs) still occur. The non-invasive fecal immunochemical …

Micro-electro-discharge machining (μEDM) plays a significant role in miniaturization.
Complex electrode manufacturing and a high wear ratio are bottlenecks for μEDM and …

Background To evaluate the cost‐effectiveness of prophylactic hysterectomy (PH) in women
with Lynch syndrome (LS). Methods We developed a microsimulation model incorporating …