HIV infection

LG Bekker, C Beyrer, N Mgodi, SR Lewin… - Nature Reviews …, 2023 - nature.com
The AIDS epidemic has been a global public health issue for more than 40 years and has
resulted in~ 40 million deaths. AIDS is caused by the retrovirus, HIV-1, which is transmitted …

The multifaceted roles of breast milk antibodies

C Atyeo, G Alter - Cell, 2021 - cell.com
Neonates are born with an immature immune system and rely on the transfer of immunity
from their mothers. Maternal antibodies are transferred via the placenta and breast milk …

The microbiota of the human mammary ecosystem

L Fernández, PS Pannaraj, S Rautava… - Frontiers in cellular and …, 2020 - frontiersin.org
Human milk contains a dynamic and complex site-specific microbiome, which is not
assembled in an aleatory way, formed by organized microbial consortia and networks …

Microbial colonization from the fetus to early childhood—a comprehensive review

V Senn, D Bassler, R Choudhury… - Frontiers in cellular …, 2020 - frontiersin.org
The development of the neonatal gastrointestinal tract microbiota remains a poorly
understood process. The interplay between neonatal (gestational age, genetic background) …

Breastmilk cell trafficking induces microchimerism‐mediated immune system maturation in the infant

JP Molès, E Tuaillon, C Kankasa… - Pediatric allergy and …, 2018 - Wiley Online Library
Initiating breastfeeding within the first hour of life confers an important benefit in terms of
child mortality and severe morbidity. Intestinal permeability to ingested macromolecules and …

72 weeks post-partum follow-up of dolutegravir versus efavirenz initiated in late pregnancy (DolPHIN-2): an open-label, randomised controlled study

TR Malaba, I Nakatudde, K Kintu, A Colbers… - The Lancet …, 2022 - thelancet.com
Background Late initiation of antiretrovirals in pregnancy is associated with increased risk of
perinatal transmission and higher infant mortality. We report the final 72-week postpartum …

[HTML][HTML] Viruses and human milk: transmission or protection?

R Francese, C Peila, M Donalisio, C Lamberti… - Advances in …, 2023 - Elsevier
Human milk (HM) is considered the best source of nutrition for infant growth and health. This
nourishment is unique and changes constantly during lactation to adapt to the physiological …

Does U= U for breastfeeding mothers and infants? Breastfeeding by mothers on effective treatment for HIV infection in high-income settings

C Waitt, N Low, P Van de Perre, F Lyons, M Loutfy… - The Lancet …, 2018 - thelancet.com
Summary Can the campaign Undetectable= Untransmittable (U= U), established for the
sexual transmission of HIV, be applied to the transmission of HIV through breastfeeding …

Extended pre-exposure prophylaxis with lopinavir–ritonavir versus lamivudine to prevent HIV-1 transmission through breastfeeding up to 50 weeks in infants in Africa …

N Nagot, C Kankasa, JK Tumwine, N Meda… - The Lancet, 2016 - thelancet.com
Background Strategies to prevent postnatal mother-to-child transmission of HIV-1 in Africa,
including infant prophylaxis, have never been assessed past 6 months of breastfeeding …

Breastfeeding with maternal antiretroviral therapy or formula feeding to prevent HIV postnatal mother-to-child transmission in Rwanda

CA Peltier, GF Ndayisaba, P Lepage, J Van Griensven… - Aids, 2009 - journals.lww.com
Objective: To assess the 9-month HIV-free survival of children with two strategies to prevent
HIV mother-to-child transmission. Design: Nonrandomized interventional cohort study …