The epithelial–mesenchymal plasticity landscape: principles of design and mechanisms of regulation

J Haerinck, S Goossens, G Berx - Nature Reviews Genetics, 2023 - nature.com
Epithelial–mesenchymal plasticity (EMP) enables cells to interconvert between several
states across the epithelial–mesenchymal landscape, thereby acquiring hybrid epithelial …

The mechanism of Warburg effect-induced chemoresistance in cancer

C Liu, Y Jin, Z Fan - Frontiers in oncology, 2021 - frontiersin.org
Although chemotherapy can improve the overall survival and prognosis of cancer patients,
chemoresistance remains an obstacle due to the diversity, heterogeneity, and adaptability to …

Circular RNA circRNF13 inhibits proliferation and metastasis of nasopharyngeal carcinoma via SUMO2

Y Mo, Y Wang, S Zhang, F Xiong, Q Yan, X Jiang… - Molecular cancer, 2021 - Springer
Abstract Background Circular RNAs (circRNAs) are widely expressed in human cells and
are closely associated with cancer development. However, they have rarely been …

The role of non‐coding RNAs in drug resistance of oral squamous cell carcinoma and therapeutic potential

X Meng, QY Lou, WY Yang, YR Wang… - Cancer …, 2021 - Wiley Online Library
Oral squamous cell carcinoma (OSCC), the eighth most prevalent cancer in the world, arises
from the interaction of multiple factors including tobacco, alcohol consumption, and betel …

LncRNAs in tumor metabolic reprogramming and immune microenvironment remodeling

J Yang, F Liu, Y Wang, L Qu, A Lin - Cancer Letters, 2022 - Elsevier
Evidence accumulated over the past decade has verified that long non-coding RNAs
(lncRNAs) exert important functions in multiple cell programs. As a novel class of cellular …

Regulation of glycolysis by non-coding RNAs in cancer: switching on the Warburg effect

H Mirzaei, MR Hamblin - Molecular Therapy-Oncolytics, 2020 - cell.com
The" Warburg effect" describes the reprogramming of glucose metabolism away from
oxidative phosphorylation toward aerobic glycolysis, and it is one of the hallmarks of cancer …

circIGHG-induced epithelial-to-mesenchymal transition promotes oral squamous cell carcinoma progression via miR-142-5p/IGF2BP3 signaling

J Liu, X Jiang, A Zou, Z Mai, Z Huang, L Sun, J Zhao - Cancer research, 2021 - AACR
Circular RNAs (circRNA) are a new member of endogenously produced noncoding RNAs
that have been characterized as key regulators of gene expression in a variety of …

[HTML][HTML] Downregulated METTL14 accumulates BPTF that reinforces super-enhancers and distal lung metastasis via glycolytic reprogramming in renal cell carcinoma

C Zhang, L Chen, Y Liu, J Huang, A Liu, Y Xu… - Theranostics, 2021 - ncbi.nlm.nih.gov
Background: Methyltransferase-like 14 (METTL14) participates in tumorigenesis in several
malignancies, but how METTL14 mediates the metastasis of renal cell carcinoma (RCC) has …

Profiling of serum exosome MiRNA reveals the potential of a MiRNA panel as diagnostic biomarker for Alzheimer's disease

Z Dong, H Gu, Q Guo, S Liang, J Xue, F Yao, X Liu… - Molecular …, 2021 - Springer
Alzheimer's disease (AD) is the most common neurodegenerative disease in the older
adults. Although much effort has been made in the analyses of diagnostic biomarkers, such …

Circle RNA hsa_circRNA_100290 serves as a ceRNA for miR‐378a to regulate oral squamous cell carcinoma cells growth via Glucose transporter‐1 (GLUT1) and …

X Chen, J Yu, H Tian, Z Shan, W Liu… - Journal of cellular …, 2019 - Wiley Online Library
Aerobic glycolysis (the Warburg effect) is a robust metabolic hallmark of most tumors,
including oral squamous cell carcinoma (OSCC). Glucose transporter 1 (GLUT1), a major …