[PDF][PDF] Guidelines for the diagnosis, treatment and prevention of leprosy

World Health Organization - 2018 - apps.who.int
The Guidelines for the Diagnosis, Treatment and Prevention of Leprosy providestate-of-the-
art knowledge and evidence on leprosy diagnosis, treatment andprevention based on a …

In search of biomarkers for leprosy by unraveling the host immune response to Mycobacterium leprae

A van Hooij, A Geluk - Immunological Reviews, 2021 - Wiley Online Library
Mycobacterium leprae, the causative agent of leprosy, is still actively transmitted in endemic
areas reflected by the fairly stable number of new cases detected each year. Recognizing …

From mouse to man: safety, immunogenicity and efficacy of a candidate leishmaniasis vaccine LEISH‐F3+ GLA‐SE

RN Coler, MS Duthie, KA Hofmeyer… - Clinical & …, 2015 - Wiley Online Library
Key antigens of Leishmania species identified in the context of host responses in
Leishmania‐exposed individuals from disease‐endemic areas were prioritized for the …

Spatial analysis spotlighting early childhood leprosy transmission in a hyperendemic municipality of the Brazilian Amazon region

JG Barreto, D Bisanzio, LS Guimaraes… - PLoS neglected …, 2014 - journals.plos.org
Background More than 200,000 new cases of leprosy were reported by 105 countries in
2011. The disease is a public health problem in Brazil, particularly within high-burden …

Mycobacterium leprae: Pathogenesis, diagnosis, and treatment options

MR Mungroo, NA Khan, R Siddiqui - Microbial Pathogenesis, 2020 - Elsevier
Mycobacterium leprae is known to cause leprosy, a neurological and dermatological
disease. In the past 20 years, 16 million leprosy cases have been recorded and more than …

Evaluation of immunodiagnostic tests for leprosy in Brazil, China and Ethiopia

A van Hooij, EM Tjon Kon Fat, M Batista da Silva… - Scientific reports, 2018 - nature.com
Leprosy remains persistently endemic in several low-or middle income countries.
Transmission is still ongoing as indicated by the unabated rate of leprosy new case …

Recent advances in gold nanoparticle-based lateral flow immunoassay for the detection of bacterial infection

Y Gupta, AS Ghrera - Archives of microbiology, 2021 - Springer
Diagnosis of bacterial infections (BI) is becoming an increasingly difficult task in clinical
practice due to their high prevalence and frequency, as well as the growth of antibiotic …

A direct method for detecting proteins in body fluids by Surface-Enhanced Raman Spectroscopy under native conditions

D Li, Z Zhang, X Wang, Y Wang, X Gao, Y Li - Biosensors and …, 2022 - Elsevier
Surface enhanced Raman spectroscopy (SERS) is widely used in biomolecular detection.
However, maintaining the native structure of proteins while obtaining sensitive and …

Immunology of leprosy

LAR Froes Jr, MAB Trindade… - International Reviews of …, 2022 - Taylor & Francis
Leprosy is a disease caused by Mycobacterium leprae (ML) with diverse clinical
manifestations, which are strongly correlated with the host's immune response. Skin lesions …

Unexpectedly high leprosy seroprevalence detected using a random surveillance strategy in midwestern Brazil: A comparison of ELISA and a rapid diagnostic test

MAC Frade, NA de Paula, CM Gomes… - PLoS Neglected …, 2017 - journals.plos.org
Background Leprosy diagnosis is mainly based on clinical evaluation, although this
approach is difficult, especially for untrained physicians. We conducted a temporary …