Therapeutic strategies to target the Ebola virus life cycle
Following the Ebola virus disease epidemic in west Africa, there has been increased
awareness of the need for improved therapies for emerging diseases, including viral …
awareness of the need for improved therapies for emerging diseases, including viral …
[HTML][HTML] Ebola virus disease: An emerging and re-emerging viral threat
The genus Ebolavirus from the family Filoviridae is composed of five species including
Sudan ebolavirus, Reston ebolavirus, Bundibugyo ebolavirus, Taï Forest ebolavirus, and …
Sudan ebolavirus, Reston ebolavirus, Bundibugyo ebolavirus, Taï Forest ebolavirus, and …
Protein interaction mapping identifies RBBP6 as a negative regulator of Ebola virus replication
Ebola virus (EBOV) infection often results in fatal illness in humans, yet little is known about
how EBOV usurps host pathways during infection. To address this, we used affinity tag …
how EBOV usurps host pathways during infection. To address this, we used affinity tag …
SCRIBER: accurate and partner type-specific prediction of protein-binding residues from proteins sequences
Motivation Accurate predictions of protein-binding residues (PBRs) enhances understanding
of molecular-level rules governing protein–protein interactions, helps protein–protein …
of molecular-level rules governing protein–protein interactions, helps protein–protein …
Designing a novel multi‑epitope vaccine against Ebola virus using reverse vaccinology approach
M Alizadeh, H Amini-Khoei, S Tahmasebian… - Scientific reports, 2022 - nature.com
Ebola virus (EBOV) is a dangerous zoonotic infectious disease. To date, more than 25 EBOV
outbreaks have been documented, the majority of which have occurred in Central Africa …
outbreaks have been documented, the majority of which have occurred in Central Africa …
Structural and functional aspects of Ebola virus proteins
S Jain, E Martynova, A Rizvanov, S Khaiboullina… - Pathogens, 2021 - mdpi.com
Ebola virus (EBOV), member of genus Ebolavirus, family Filoviridae, have a non-segmented,
single-stranded RNA that contains seven genes:(a) nucleoprotein (NP),(b) viral protein 35 …
single-stranded RNA that contains seven genes:(a) nucleoprotein (NP),(b) viral protein 35 …
Post-exposure treatments for Ebola and Marburg virus infections
RW Cross, CE Mire, H Feldmann… - Nature Reviews Drug …, 2018 - nature.com
The filoviruses—Ebola virus and Marburg virus—cause lethal haemorrhagic fever in
humans and non-human primates (NHPs). Filoviruses present a global health threat both as …
humans and non-human primates (NHPs). Filoviruses present a global health threat both as …
Filoviruses: ecology, molecular biology, and evolution
J Emanuel, A Marzi, H Feldmann - Advances in virus research, 2018 - Elsevier
The Filoviridae are a family of negative-strand RNA viruses that include several important
human pathogens. Ebola virus (EBOV) and Marburg virus are well-known filoviruses which …
human pathogens. Ebola virus (EBOV) and Marburg virus are well-known filoviruses which …
New perspectives on the biogenesis of viral inclusion bodies in negative-sense RNA virus infections
O Dolnik, GK Gerresheim, N Biedenkopf - Cells, 2021 - mdpi.com
Infections by negative strand RNA viruses (NSVs) induce the formation of viral inclusion
bodies (IBs) in the host cell that segregate viral as well as cellular proteins to enable efficient …
bodies (IBs) in the host cell that segregate viral as well as cellular proteins to enable efficient …
Ebola virus proteins NP, VP35, and VP24 are essential and sufficient to mediate nucleocapsid transport
Y Takamatsu, L Kolesnikova… - Proceedings of the …, 2018 - National Acad Sciences
The intracytoplasmic movement of nucleocapsids is a crucial step in the life cycle of
enveloped viruses. Determination of the viral components necessary for viral nucleocapsid …
enveloped viruses. Determination of the viral components necessary for viral nucleocapsid …