Obesity and cancer risk: Emerging biological mechanisms and perspectives
Continuously rising trends in obesity-related malignancies render this disease spectrum a
public health priority. Worldwide, the burden of cancer attributable to obesity, expressed as …
public health priority. Worldwide, the burden of cancer attributable to obesity, expressed as …
Cancer chemoprevention by caroteno
T Tanaka, M Shnimizu, H Moriwaki - Molecules, 2012 - mdpi.com
Carotenoids are natural fat-soluble pigments that provide bright coloration to plants and
animals. Dietary intake of carotenoids is inversely associated with the risk of a variety of …
animals. Dietary intake of carotenoids is inversely associated with the risk of a variety of …
Risk of prostate cancer–specific mortality following biochemical recurrence after radical prostatectomy
SJ Freedland, EB Humphreys, LA Mangold… - Jama, 2005 - jamanetwork.com
ContextThe natural history of biochemical recurrence after radical prostatectomy can be long
but variable. Better risk assessment models are needed to identify men who are at high risk …
but variable. Better risk assessment models are needed to identify men who are at high risk …
Role of the insulin-like growth factor family in cancer development and progression
H Yu, T Rohan - Journal of the National Cancer Institute, 2000 - academic.oup.com
The insulin-like growth factors (IGFs) are mitogens that play a pivotal role in regulating cell
proliferation, differentiation, and apoptosis. The effects of IGFs are mediated through the IGF …
proliferation, differentiation, and apoptosis. The effects of IGFs are mediated through the IGF …
Plasma insulin-like growth factor-I and prostate cancer risk: a prospective study
JM Chan, MJ Stampfer, E Giovannucci, PH Gann, J Ma… - Science, 1998 - science.org
Insulin-like growth factor–I (IGF-I) is a mitogen for prostate epithelial cells. To investigate
associations between plasma IGF levels and prostate cancer risk, a nested case-control …
associations between plasma IGF levels and prostate cancer risk, a nested case-control …
Biology of prostate-specific antigen
SP Balk, YJ Ko, GJ Bubley - Journal of clinical oncology, 2003 - ascopubs.org
Prostate-specific antigen (PSA) is an androgen-regulated serine protease produced by both
prostate epithelial cells and prostate cancer (PCa) and is the most commonly used serum …
prostate epithelial cells and prostate cancer (PCa) and is the most commonly used serum …
The role of carotenoids in the prevention of human pathologies
H Tapiero, DM Townsend, KD Tew - Biomedicine & Pharmacotherapy, 2004 - Elsevier
Reactive oxygen species (ROS) and oxidative damage to biomolecules have been
postulated to be involved in the causation and progression of several chronic diseases …
postulated to be involved in the causation and progression of several chronic diseases …
Diabetes mellitus as a predictor of cancer mortality in a large cohort of US adults
SS Coughlin, EE Calle, LR Teras… - American journal of …, 2004 - academic.oup.com
Several studies have suggested that diabetes mellitus may alter the risk of developing a
variety of cancers, and the associations are biologically plausible. To learn more about the …
variety of cancers, and the associations are biologically plausible. To learn more about the …
The effects of insulin-like growth factors on tumorigenesis and neoplastic growth
HM Khandwala, IE McCutcheon, A Flyvbjerg… - Endocrine …, 2000 - academic.oup.com
Several decades of basic and clinical research have demonstrated that there is an
association between the insulin-like growth factors (IGFs) and neoplasia. We begin with a …
association between the insulin-like growth factors (IGFs) and neoplasia. We begin with a …
Lignans and human health
H Adlercreutz - Critical reviews in clinical laboratory sciences, 2007 - Taylor & Francis
This review focuses on the possible role in human health of the consumption of lignan-rich
foods. Most of the plant lignans in human foods are converted by the intestinal microflora in …
foods. Most of the plant lignans in human foods are converted by the intestinal microflora in …