Applications of tandem mass spectrometry (MS/MS) in protein analysis for biomedical research

AN Neagu, M Jayathirtha, E Baxter, M Donnelly… - Molecules, 2022 - mdpi.com
Mass Spectrometry (MS) allows the analysis of proteins and peptides through a variety of
methods, such as Electrospray Ionization-Mass Spectrometry (ESI-MS) or Matrix-Assisted …

Redefining modern food analysis: significance of omics analytical techniques integration, chemometrics and bioinformatics

CO Okoye, H Jiang, M Nazar, XL Tan, J Jiang - TrAC Trends in Analytical …, 2024 - Elsevier
Food analysis is a scientific discipline that has evolved from traditional methods into
sophisticated approaches due to advances in analytical chemistry and modern …

A comparison of tissue dissection techniques for diagnostic, prognostic, and theragnostic analysis of human disease

EM Walsh, MK Halushka - Pathobiology, 2023 - karger.com
Histopathology has historically been the critical technique for the diagnosis and treatment of
human disease. Today, genomics, transcriptomics, and proteomics from specific cells, rather …

Biomarker Analysis of Formalin-Fixed Paraffin-Embedded Clinical Tissues Using Proteomics

EN Obi, DA Tellock, GJ Thomas, TD Veenstra - Biomolecules, 2023 - mdpi.com
The relatively recent developments in mass spectrometry (MS) have provided novel
opportunities for this technology to impact modern medicine. One of those opportunities is in …

Inter-Regional Proteomic Profiling of the Human Brain Using an Optimized Protein Extraction Method from Formalin-Fixed Tissue to Identify Signaling Pathways

JM Davidson, SL Rayner, S Liu, F Cheng… - International Journal of …, 2023 - mdpi.com
Proteomics offers vast potential for studying the molecular regulation of the human brain.
Formalin fixation is a common method for preserving human tissue; however, it presents …

Differential Expression of Proteins Associated with Bipolar Disorder as Identified Using the PeptideShaker Software

AA Seregin, LP Smirnova, EM Dmitrieva… - International Journal of …, 2023 - mdpi.com
The prevalence of bipolar disorder (BD) in modern society is growing rapidly, but due to the
lack of paraclinical criteria, its differential diagnosis with other mental disorders is somewhat …

Effect of polyethylene glycol 20 000 on protein extraction efficiency of formalin-fixed paraffin-embedded tissues in South Africa

S Rossouw, H Bendou, L Bell, J Rigby… - African Journal of …, 2021 - journals.co.za
Background Optimal protocols for efficient and reproducible protein extraction from formalin-
fixed paraffin-embedded (FFPE) tissues are not yet standardised and new techniques are …

Approach to personalized medicine in endometrial cancer for the control of recurrent disease

C López Gil - 2022 - ddd.uab.cat
Endometrial cancer (EC) is the second most frequent gynecological cancer worldwide. In
general, most patients are diagnosed at early stages of the disease with an overall 5-years …