Ischemic heart disease (IHD) is the leading cause of mortality in women. While traditional
cardiovascular risk factors play an important role in the development of IHD in women …

Abstract The Bifurcation Academic Research Consortium (Bif-ARC) project originated from
the need to overcome the paucity of standardization and comparability between studies …

Objectives The aim of this study was to compare Doppler flow velocity and thermodilution-
derived indexes and to determine the optimal thermodilution-based diagnostic thresholds for …

Objectives This study assessed the ability to identify coronary microvascular dysfunction
(CMD) in patients with angina and nonobstructive coronary artery disease (NOCAD) using …

Background Coronary microvascular dysfunction (CMD) is an important contributor to
angina syndromes. Recently, two distinct endotypes were identified using combined …

Coronary microvascular disease (CMD), characterized by impaired coronary flow reserve
(CFR), is a common finding in patients with stable angina. Impaired CFR, in the absence of …

Nitric oxide (NO) plays an important and diverse signalling role in the cardiovascular system,
contributing to the regulation of vascular tone, endothelial function, myocardial function …

Background: Coronary microvascular function can be distinctly quantified using the coronary
flow reserve (CFR) and index of microvascular resistance (IMR). Patients with low CFR can …

Coronary microvascular disease (CMD) causes myocardial ischemia in a variety of clinical
scenarios. Clinical practice guidelines support routine testing for CMD in patients with …

Heart failure with preserved ejection fraction (HFpEF) currently accounts for approximately
half of all new heart failure cases in the community. HFpEF is closely associated with chronic …