Obesity, a pandemic of the modern world, is intimately associated with dyslipidemia, which
is mainly driven by the effects of insulin resistance and pro-inflammatory adipokines …

Since the discovery of proprotein convertase subtilisin kexin 9 (PCSK9) in 2003, this PC has
attracted a lot of attention from the scientific community and pharmaceutical companies …

Objective Development of these guidelines is mandated by the American Association of
Clinical Endocrinologists (AACE) Board of Directors and the American College of …

Cardiovascular (CV) disease is a leading cause of death worldwide, accounting for
approximately 31.4% of deaths globally in 2012. It is estimated that, from 1980 to 2000 …

The term “fat” may refer to lipids as well as the cells and tissue that store lipid (ie, adipocytes
and adipose tissue).“Lipid” is derived from “lipos,” which refers to animal fat or vegetable oil …

PCSK9 is an established target for cholesterol-lowering therapies. Further study of PCSK9
regulatory mechanisms may identify additional control points for pharmacological inhibition …

The Mediterranean Diet (MedDiet) has been reported to be protective against the
occurrence of several diseases. Increasing evidence suggests that the MedDiet could …

Cholesterol plays a vital role in the human body as a precursor of steroid hormones and bile
acids, in addition to providing structure to cell membranes. Whole body cholesterol …

Sleep duration and sleep quality are important predictors of risk for cardiovascular disease
(CVD). One potential link between sleep health and CVD is through lifestyle factors such as …

Metabolic syndrome (MetS) is a cluster of metabolic abnormalities characterized by central
obesity, dyslipidemias, hypertension, high fasting glucose, chronic low-grade inflammation …