A brief review of influenza virus infection

M Javanian, M Barary, S Ghebrehewet… - Journal of medical …, 2021 - Wiley Online Library
Influenza is an acute viral respiratory infection that affects all age groups and is associated
with high mortality during pandemics, epidemics, and sporadic outbreaks. Nearly 10% of the …

[HTML][HTML] Carbohydrate-based drugs launched during 2000− 2021

X Cao, X Du, H Jiao, Q An, R Chen, P Fang… - … Pharmaceutica Sinica B, 2022 - Elsevier
Carbohydrates are fundamental molecules involved in nearly all aspects of lives, such as
being involved in formating the genetic and energy materials, supporting the structure of …

Avian influenza viruses in humans: lessons from past outbreaks

YT Li, M Linster, IH Mendenhall, YCF Su… - British Medical …, 2019 - academic.oup.com
Background Human infections with avian influenza viruses (AIV) represent a persistent
public health threat. The principal risk factor governing human infection with AIV is from …

Overview of current therapeutics and novel candidates against influenza, respiratory syncytial virus, and Middle East respiratory syndrome coronavirus infections

MA Behzadi, VH Leyva-Grado - Frontiers in microbiology, 2019 - frontiersin.org
Emergence and re-emergence of respiratory virus infections represent a significant threat to
global public health, as they occur seasonally and less frequently (such as in the case of …

Evolution of influenza viruses—drug resistance, treatment options, and prospects

JM Smyk, N Szydłowska, W Szulc… - International Journal of …, 2022 - mdpi.com
Viral evolution refers to the genetic changes that a virus accumulates during its lifetime
which can arise from adaptations in response to environmental changes or the immune …

Development of effective anti-influenza drugs: congeners and conjugates–a review

JJ Shie, JM Fang - Journal of Biomedical Science, 2019 - Springer
Influenza is a long-standing health problem. For treatment of seasonal flu and possible
pandemic infections, there is a need to develop new anti-influenza drugs that have good …

High throughput virtual screening reveals SARS-CoV-2 multi-target binding natural compounds to lead instant therapy for COVID-19 treatment

B Naik, N Gupta, R Ojha, S Singh, VK Prajapati… - International Journal of …, 2020 - Elsevier
The present-day world is severely suffering from the recently emerged SARS-CoV-2. The
lack of prescribed drugs for the deadly virus has stressed the likely need to identify novel …

Chemical synthesis of oligosaccharides and their application in new drug research

Z Lv, H Liu, H Hao, FU Rahman, Y Zhang - European Journal of Medicinal …, 2023 - Elsevier
Oligosaccharides are the ubiquitous molecules of life. In order to translate human
bioglycosylation into clinical applications, homogeneous samples of oligosaccharides and …

[HTML][HTML] Influenza viruses–antiviral therapy and resistance

S Duwe - GMS infectious diseases, 2017 - ncbi.nlm.nih.gov
Influenza is a serious and frequently underestimated, but vaccine preventable disease. The
adamantane derivates rimantadine and amantadine and the neuraminidase inhibitors …

Antivirals targeting the surface glycoproteins of influenza virus: Mechanisms of action and resistance

Y Bai, JC Jones, SS Wong, M Zanin - Viruses, 2021 - mdpi.com
Hemagglutinin and neuraminidase, which constitute the glycoprotein spikes expressed on
the surface of influenza A and B viruses, are the most exposed parts of the virus and play …