The sensitivity and costs of testing for SARS-CoV-2 infection with saliva versus nasopharyngeal swabs: a systematic review and meta-analysis

ML Bastos, S Perlman-Arrow, D Menzies… - Annals of internal …, 2021 - acpjournals.org
Background: Nasopharyngeal swabs are the primary sampling method used for detection of
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), but they require a trained …

Two years into the COVID-19 pandemic: lessons learned

SJR da Silva, JCF do Nascimento… - ACS infectious …, 2022 - ACS Publications
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly transmissible
and virulent human-infecting coronavirus that emerged in late December 2019 in Wuhan …

Comparison of saliva and nasopharyngeal swab nucleic acid amplification testing for detection of SARS-CoV-2: a systematic review and meta-analysis

G Butler-Laporte, A Lawandi, I Schiller… - JAMA internal …, 2021 - jamanetwork.com
Importance Nasopharyngeal swab nucleic acid amplification testing (NAAT) is the
noninvasive criterion standard for diagnosis of coronavirus disease 2019 (COVID-19) …

SARS-CoV-2 variants of concern Alpha and Delta show increased viral load in saliva

KL King, S Wilson, JM Napolitano, KJ Sell, L Rennert… - PLoS …, 2022 - journals.plos.org
Background Higher viral loads in SARS-CoV-2 infections may be linked to more rapid
spread of emerging variants of concern (VOC). Rapid detection and isolation of cases with …

Smartphone-based sensitive detection of SARS-CoV-2 from saline gargle samples via flow profile analysis on a paper microfluidic chip

P Akarapipad, K Kaarj, LE Breshears… - Biosensors and …, 2022 - Elsevier
Respiratory viruses, especially coronaviruses, have resulted in worldwide pandemics in the
past couple of decades. Saliva-based paper microfluidic assays represent an opportunity for …

[HTML][HTML] SARS-CoV-2 diagnostics based on nucleic acids amplification: from fundamental concepts to applications and beyond

JM Vindeirinho, E Pinho, NF Azevedo… - Frontiers in cellular and …, 2022 - frontiersin.org
Covid-19 pandemic ignited the development of countless molecular methods for the
diagnosis of SARS-CoV-2 based either on nucleic acid, or protein analysis, with the first …

High efficacy of saliva in detecting SARS-CoV-2 by RT-PCR in adults and children

M Huber, PW Schreiber, T Scheier, A Audigé… - Microorganisms, 2021 - mdpi.com
Rising demands for repetitive SARS-CoV-2 screens and mass testing necessitate additional
test strategies. Saliva may serve as an alternative to nasopharyngeal swab (NPS) as its …

Prevalence of RT-qPCR-detected SARS-CoV-2 infection at schools: First results from the Austrian School-SARS-CoV-2 prospective cohort study

P Willeit, R Krause, B Lamprecht… - The Lancet Regional …, 2021 - thelancet.com
Background The role of schools in the SARS-CoV-2 pandemic is much debated. We aimed
to quantify reliably the prevalence of SARS-CoV-2 infections at schools detected with …

Generation of false-positive SARS-CoV-2 antigen results with testing conditions outside manufacturer recommendations: a scientific approach to pandemic …

G Patriquin, RJ Davidson, TF Hatchette… - Microbiology …, 2021 - Am Soc Microbiol
Antigen-based rapid diagnostics tests (Ag-RDTs) are useful tools for severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) detection. However, misleading …

Saliva as a sample type for SARS-CoV-2 detection: implementation successes and opportunities around the globe

ER Tobik, LB Kitfield-Vernon, RJ Thomas… - Expert Review of …, 2022 - Taylor & Francis
Introduction Symptomatic testing and asymptomatic screening for SARS-CoV-2 continue to
be essential tools for mitigating virus transmission. Though COVID-19 diagnostics initially …