Anti-inflammatory microRNAs and their potential for inflammatory diseases treatment

A Tahamtan, M Teymoori-Rad, B Nakstad… - Frontiers in …, 2018 - frontiersin.org
Inflammation is a complicated biological and pathophysiological cascade of responses to
infections and injuries, and inflammatory mechanisms are closely related to many diseases …

Molecular mechanisms of innate memory and tolerance to LPS

JJ Seeley, S Ghosh - Journal of Leucocyte Biology, 2017 - academic.oup.com
LPS is a potent trigger of macrophage-mediated inflammation. However, prolonged
exposure to LPS induces a state of tolerance that reprograms the inflammatory response …

MicroRNAs: history, biogenesis, and their evolving role in animal development and disease

M Bhaskaran, M Mohan - Veterinary pathology, 2014 - journals.sagepub.com
The discovery of microRNAs (miRNAs) in 1993 followed by developments and discoveries
in small RNA biology have redefined the biological landscape by significantly altering the …

MicroRNA-223 controls susceptibility to tuberculosis by regulating lung neutrophil recruitment

A Dorhoi, M Iannaccone, M Farinacci… - The Journal of …, 2013 - Am Soc Clin Investig
The molecular mechanisms that control innate immune cell trafficking during chronic
infection and inflammation, such as in tuberculosis (TB), are incompletely understood …

MicroRNA let-7 modulates the immune response to Mycobacterium tuberculosis infection via control of A20, an inhibitor of the NF-κB pathway

M Kumar, SK Sahu, R Kumar, A Subuddhi, RK Maji… - Cell host & …, 2015 - cell.com
The outcome of the interaction between Mycobacterium tuberculosis (Mtb) and a
macrophage depends on the interplay between host defense and bacterial immune …

miRNAs reshape immunity and inflammatory responses in bacterial infection

X Zhou, X Li, M Wu - Signal transduction and targeted therapy, 2018 - nature.com
Pathogenic bacteria cause various infections worldwide, especially in immunocompromised
and other susceptible individuals, and are also associated with high infant mortality rates in …

Progress in tuberculosis vaccine development and host-directed therapies—a state of the art review

SHE Kaufmann, C Lange, M Rao, KN Balaji… - The Lancet …, 2014 - thelancet.com
Tuberculosis continues to kill 1· 4 million people annually. During the past 5 years, an
alarming increase in the number of patients with multidrug-resistant tuberculosis and …

Micro rna s and bacterial infection

C Staedel, F Darfeuille - Cellular microbiology, 2013 - Wiley Online Library
Micro RNA s, small non‐coding RNAs expressed by eukaryotic cells, play pivotal roles in
shaping cell differentiation and organism development. Deregulated micro RNA expression …

Different modalities of host cell death and their impact on Mycobacterium tuberculosis infection

A Nisa, FC Kipper, D Panigrahy… - … of Physiology-Cell …, 2022 - journals.physiology.org
Mycobacterium tuberculosis (Mtb) is the pathogen that causes tuberculosis (TB), a leading
infectious disease of humans worldwide. One of the main histopathological hallmarks of TB …

SARS-CoV-2 may regulate cellular responses through depletion of specific host miRNAs

R Bartoszewski, M Dabrowski… - … of Physiology-Lung …, 2020 - journals.physiology.org
Cold viruses have generally been considered fairly innocuous until the appearance of the
severe acute respiratory coronavirus 2 (SARS-CoV-2) in 2019, which caused the …