Research into Alzheimer's Disease (AD) describes a link between AD and the resident
immune cells of the brain, the microglia. Further, this suspected link is thought to have …

In females, Alzheimer's disease (AD) incidences increases as compared to males due to
estrogen deficiency after menopause. Estrogen therapy is the mainstay therapy for …

Background Intervertebral disc degeneration (IDD) is a major cause of low back pain (LBP)
worldwide. Sexual dimorphism, or sex‐based differences, appear to exist in the severity of …

Alzheimer's disease (AD) is the leading cause of dementia and is characterized by a
progressive decline in cognitive abilities. A pathological hallmark of AD is a region-specific …

Background Amyloid beta (Aβ) plaque density was examined in the amygdala of rhesus
macaques, to elucidate the influence of age, diet and hormonal environment. Methods …

Abstract Alzheimer's disease (AD), a multi-factorial neurodegenerative disorder has affected
over 30 million individuals globally and these numbers are expected to increase in the …

Alzheimer's disease (AD) represents an urgent yet unmet challenge for modern society,
calling for exploration of innovative targets and therapeutic approaches. Astrocytes, main …

The lack of affordable and effective therapeutics against cognitive impairment has promoted
research toward alternative approaches to the treatment of neurodegeneration. In recent …

Amyloid-β (Aβ) and tau proteins accumulate within distinct neuronal systems in Alzheimer's
disease (AD). Although it is not clear why certain brain regions are more vulnerable to Aβ …

In the last years, many clinical studies highlighted sex-specific differences in the
pathophysiology of Alzheimer's disease (AD). The recent paper published in the Journal of …