The microvascular endothelial cell monolayer localized at the critical interface between the
blood and vessel wall has the vital functions of regulating tissue fluid balance and supplying …

The endothelium functions as a semipermeable barrier regulating tissue fluid homeostasis
and transmigration of leukocytes and providing essential nutrients across the vessel wall …

The ConSurf web‐sever for the analysis of proteins, RNA, and DNA provides a quick and
accurate estimate of the per‐site evolutionary rate among homologues. The analysis reveals …

Emerging evidence suggests that extracellular vesicle (EV)–containing miRNAs mediate
intercellular communications in response to noxious stimuli. It remains unclear how a cell …

Although they were discovered more than 50 years ago, caveolae have remained enigmatic
plasmalemmal organelles. With their characteristic “flasklike” shape and virtually ubiquitous …

The caveolin gene family has three members in vertebrates: caveolin-1, caveolin-2, and
caveolin-3. So far, most caveolin-related research has been conducted in mammals, but the …

Cellular organelles have characteristic morphologies that arise as a result of different local
membrane curvatures. A striking example is the endoplasmic reticulum (ER), which consists …

Caveolae are specialized lipid rafts that form flask-shaped invaginations of the plasma
membrane. They are involved in cell signalling and transport and have been shown critically …

To investigate whether caveolae are involved in constitutive endocytic trafficking, we
expressed N-and C-terminally green fluorescent protein (GFP)-tagged caveolin-1 fusion …

Recent evidence supports the existence of a plasma membrane ER. In many cells, E2
activates signal transduction and cell proliferation, but the steroid inhibits signaling and …