Review of Hair Follicle Dermal Papilla cells as in vitro screening model for hair growth

A Madaan, R Verma, AT Singh… - International journal of …, 2018 - Wiley Online Library
Hair disorders such as hair loss (alopecia) and androgen dependent, excessive hair growth
(hirsutism, hypertrichosis) may impact the social and psychological well‐being of an …

Small Molecule Agents Against Alopecia: Potential Targets and Related Pathways

X Luo, X Ni, J Zhi, X Jiang, R Bai - European Journal of Medicinal Chemistry, 2024 - Elsevier
Alopecia has emerged as a global concern, extending beyond the middle-aged and elderly
population and increasingly affecting younger individuals. Despite its growing prevalence …

Efficacy of 5% minoxidil versus combined 5% minoxidil and 0.01% tretinoin for male pattern hair loss: a randomized, double-blind, comparative clinical trial

HS Shin, CH Won, SH Lee, OS Kwon, KH Kim… - American journal of …, 2007 - Springer
Background: 5% topical minoxidil solution has been widely used to stimulate new hair
growth and help stop hair loss in men with androgenetic alopecia (AGA). However, it is not …

Tretinoin enhances minoxidil response in androgenetic alopecia patients by upregulating follicular sulfotransferase enzymes

A Sharma, A Goren, R Dhurat, S Agrawal… - Dermatologic …, 2019 - Wiley Online Library
Minoxidil sulfate is the active metabolite required to exert the vasodilatory and hair growing
effects of minoxidil. For hair growth, sulfotransferase enzymes expressed in outer root …

Minoxidil downregulates interleukin-1 alpha gene expression in HaCaT cells

E Pekmezci, M Turkoğlu, H Gökalp… - International journal of …, 2018 - journals.lww.com
Materials and Methods: Cellular proliferation was examined using the Cell Proliferation Kit II
(XTT) reagent. After determining a noncytotoxic concentration, HaCaT cells were treated …

Retinol/inflammation affect stemness and differentiation potential of gingival stem/progenitor cells via Wnt/β‐catenin

KM Fawzy El‐Sayed, D Hein… - Journal of Periodontal …, 2019 - Wiley Online Library
Background and objective Inflammatory cytokines impact the course of periodontal disease,
repair, and regeneration. Vitamin A and its metabolites are inflammation‐modulatory …

The microfollicle: a model of the human hair follicle for in vitro studies

B Ataç, FM Kiss, T Lam, B Fauler, C Edler, P Hu… - In Vitro Cellular & …, 2020 - Springer
Access to complex in vitro models that recapitulate the unique markers and cell-cell
interactions of the hair follicle is rather limited. Creation of scalable, affordable, and relevant …

Ascorbic acid/retinol and/or inflammatory stimuli's effect on proliferation/differentiation properties and transcriptomics of gingival stem/progenitor cells

KM Fawzy El-Sayed, A Bittner, K Schlicht, M Mekhemar… - Cells, 2021 - mdpi.com
The present study explored the effects of ascorbic-acid (AA)/retinol and timed inflammation
on the stemness, the regenerative potential, and the transcriptomics profile of gingival …

Hydroxytyrosol prevents dermal papilla cells inflammation under oxidative stress by inducing autophagy

Q Chen, T Sun, J Wang, J Jia, YH Yi… - … of Biochemical and …, 2019 - Wiley Online Library
Hydroxytyrosol (HT), a primary phenolic antioxidant in olive oil, can afford protection from
oxidative stress (OS) in different cells, including skin cells. In particular, it regulates several …

Experimental and early investigational drugs for androgenetic alopecia

H Guo, WV Gao, H Endo… - Expert opinion on …, 2017 - Taylor & Francis
Introduction: Treatments for androgenetic alopecia constitute a multi-billion-dollar industry,
however, currently available therapeutic options have variable efficacy. Consequently, in …