Engineering microneedle patches for improved penetration: analysis, skin models and factors affecting needle insertion

P Makvandi, M Kirkby, ARJ Hutton, M Shabani… - Nano-Micro Letters, 2021 - Springer
Transdermal microneedle (MN) patches are a promising tool used to transport a wide variety
of active compounds into the skin. To serve as a substitute for common hypodermic needles …

Current trends in polymer microneedle for transdermal drug delivery

KAS Al-Japairai, S Mahmood, SH Almurisi… - International journal of …, 2020 - Elsevier
Transdermal drug delivery using microneedles is increasingly gaining interest due to the
issues associated with oral drug delivery routes. Gastrointestinal route exposes the drug to …

Advances in antimicrobial microneedle patches for combating infections

R Jamaledin, CKY Yiu, EN Zare, LN Niu… - Advanced …, 2020 - Wiley Online Library
Skin infections caused by bacteria, viruses and fungi are difficult to treat by conventional
topical administration because of poor drug penetration across the stratum corneum. This …

3D-printed microneedles in biomedical applications

SR Dabbagh, MR Sarabi, R Rahbarghazi, E Sokullu… - Iscience, 2021 - cell.com
Conventional needle technologies can be advanced with emerging nano-and micro-
fabrication methods to fabricate microneedles. Nano-/micro-fabricated microneedles seek to …

Design principles of microneedles for drug delivery and sampling applications

Z Le, J Yu, YJ Quek, B Bai, X Li, Y Shou, B Myint, C Xu… - Materials Today, 2023 - Elsevier
Microneedles technology is a powerful platform to achieve efficient transdermal delivery of
bioactive molecules for local or systemic therapies attributing to their minimally invasive …

Wearable Clinic: From Microneedle‐Based Sensors to Next‐Generation Healthcare Platforms

H Sun, Y Zheng, G Shi, H Haick, M Zhang - Small, 2023 - Wiley Online Library
The rapid development of wearable biosensing calls for next‐generation devices that allow
continuous, real‐time, and painless monitoring of health status along with responsive …

Dissolvable polymer microneedles for drug delivery and diagnostics

M Ali, S Namjoshi, HAE Benson, Y Mohammed… - Journal of Controlled …, 2022 - Elsevier
Dissolvable transdermal microneedles (μND) are promising micro-devices used to transport
a wide selection of active compounds into the skin. To provide an effective therapeutic …

3D printing as a transformative tool for microneedle systems: Recent advances, manufacturing considerations and market potential

SN Economidou, D Douroumis - Advanced Drug Delivery Reviews, 2021 - Elsevier
The present review aims at identifying the key progress points that have been made on the
use of 3D printing to manufacture microneedles in the past 3 years. The advances in the …

[HTML][HTML] Biosensing in dermal interstitial fluid using microneedle based electrochemical devices

J Madden, C O'Mahony, M Thompson… - Sensing and Bio …, 2020 - Elsevier
This article explores recent advances in the development of electrochemical biosensors on
microneedle platforms towards on-device sensing of biomarkers present in dermal interstitial …

A review of 3D-printing of microneedles

M Olowe, SK Parupelli, S Desai - Pharmaceutics, 2022 - mdpi.com
Microneedles are micron-sized devices that are used for the transdermal administration of a
wide range of active pharmaceutics substances with minimally invasive pain. In the past …