Inhaled toxicants are used for diverse purposes, ranging from industrial applications such as
agriculture, sanitation, and fumigation to crowd control and chemical warfare, and acute …

Most mortality and morbidity following exposure to vesicants such as sulfur mustard is due to
pulmonary toxicity. Acute injury is characterized by epithelial detachment and necrosis in the …

This report is based on the proceedings from the Inhalational Lung Injury Workshop jointly
sponsored by the American Thoracic Society (ATS) and the National Institutes of Health …

Background. Pulmonary ischemia reperfusion‐(I/R‐) induced dysfunction is a significant
clinical problem after lung transplantation. In this study, we aim to explore the molecular …

Sulfur mustard (SM) is a chemical alkylating compound that primary targets lung tissue. It
causes a wide variety of pathological effects in respiratory system such as chronic bronchitis …

Acute lung injury due to sulfur mustard (SM) inhalation causes the formation of airway fibrin
casts that obstruct airways at multiple levels, leading to acute respiratory failure and death …

Rationale: Sulfur mustard (SM) is a chemical weapon stockpiled today in volatile regions of
the world. SM inhalation causes a life-threatening airway injury characterized by airway …

Sulfur mustard (SM) is a highly toxic war chemical that causes significant morbidity and
mortality and lacks any effective therapy. Rats exposed to aerosolized CEES (2-chloroethyl …

Tissue factor (TF)-dependent coagulation contributes to lung inflammation and the
pathogenesis of acute lung injury (ALI). In this study, we explored the roles of targeted …

Sulfur mustard and related vesicants are cytotoxic alkylating agents that cause severe
damage to the respiratory tract. Injury is progressive leading, over time, to asthma …