Fatty liver diseases, which are commonly associated with high-fat/calorie diet, heavy alcohol
consumption and/or other metabolic disorder causes, lead to serious medical concerns …

Lycopene is a lipophilic, unsaturated carotenoid, found in red-colored fruits and vegetables,
including tomatoes, watermelon, papaya, red grapefruits, and guava. The present work …

A ketogenic diet (KD; high-fat, low-carbohydrate) can benefit refractory epilepsy, but
underlying mechanisms are unknown. We used mice inducibly expressing a mutated form of …

This review examines the shared immune-inflammatory, oxidative and nitrosative stress
(IO&NS) and metabolic pathways underpinning metabolic syndrome (MetS), bipolar disorder …

Vitamin A was recognized as an essential nutrient 100 years ago. In the 1930s, it became
clear that dietary β-carotene was cleaved at its central double to yield vitamin A (retinal or β …

Turmeric has been long recognized for its anti‐inflammatory and health‐promoting
properties. Curcumin is one of the principal anti‐inflammatory and healthful components of …

Abstract Sirtuin 1 (SIRT1), the mammalian ortholog of yeast Sir2, is a highly conserved
NAD+-dependent protein deacetylase that has emerged as a key metabolic sensor that …

Sirtuins are highly conserved NAD+-dependent protein deacetylases and/or ADP-
ribosyltransferases that can extend the lifespan of several lower model organisms including …

Cells evolve to actively coordinate nutrient availability with cellular activity in order to
maintain metabolic homeostasis. In addition, active pathways to repair DNA damage are …

Turmeric (Curcuma longa) is a rhizomatous herbaceous perennial plant of the ginger family
which has been used to treat biliary disorders, anorexia, cough, rheumatism, cancer …