A salivary gland resident macrophage subset regulating radiation responses

Q Zhao, S Pan, L Zhang, Y Zhang… - Journal of Dental …, 2023 - journals.sagepub.com
Radiotherapy of head and neck cancers frequently leads to irreversible hypofunction of
salivary glands, which severely compromises the quality of life and is extremely difficult to …

[HTML][HTML] Intragland Expression of the Shh Gene Alleviates Irradiation-Induced Salivary Gland Injury through Microvessel Protection and the Regulation of Oxidative …

M Hu, L Hu, T Yang, B Zhou, X Feng, Z Fan, Z Shan - Antioxidants, 2024 - mdpi.com
Radiation-induced salivary gland injury (RISGI) is a common complication of radiotherapy in
patients with head and neck cancer. Intragland expression of the Sonic Hedgehog (Shh) …

PANoptosis induced by inflammatory cytokines promotes salivary glands radiation injury

Y Qu, D Li, G Chen, S Zhao, Z Han, L Qin - Oral Diseases, 2024 - Wiley Online Library
Objective Salivary glands are frequently damaged in patients undergoing radiotherapy for
head and neck cancer. Whether PANoptosis, which is characterized by pyroptosis …

Effect of silencing SSB1 gene on the expression of NBS1 in irradiated rat submandibular gland cells

L Gao, Q Lv, Y Huang, Y Fan, L Zhao… - Cellular and …, 2024 - mail.cellmolbiol.org
The salivary gland (SGS) is a kind of organ vulnerable to ionizing radiation. Radiotherapy is
an important treatment for head and neck tumors, but in the process of radiotherapy, tumor …

Effect of Ionizing Radiation Exposure on NOX4 Expression in-Vitro and in-Vivo Studies: A Systematic Review and Meta-analysis

P Hajimirzaei, R Paydar, M Razmgir, F Rajabinasab… - 2024 - researchsquare.com
Introduction: Patients exposed to ionizing radiation (IR) from various sources experience
several side effects. Understanding the mechanisms through which IR induces these effects …