Dynamics and mechanisms of CNS myelination
KK Bercury, WB Macklin - Developmental cell, 2015 - cell.com
Vertebrate myelination is an evolutionary advancement essential for motor, sensory, and
higher-order cognitive function. CNS myelin, a multilamellar differentiation of the …
higher-order cognitive function. CNS myelin, a multilamellar differentiation of the …
[HTML][HTML] Glial-neuron crosstalk in health and disease: A focus on metabolism, obesity, and cognitive impairment
Dementia is a complex set of disorders affecting normal cognitive function. Recently, several
clinical studies have shown that diabetes, obesity, and components of the metabolic …
clinical studies have shown that diabetes, obesity, and components of the metabolic …
[HTML][HTML] Human iPSC glial mouse chimeras reveal glial contributions to schizophrenia
In this study, we investigated whether intrinsic glial dysfunction contributes to the
pathogenesis of schizophrenia (SCZ). Our approach was to establish humanized glial …
pathogenesis of schizophrenia (SCZ). Our approach was to establish humanized glial …
The astrocyte: powerhouse and recycling center
Brain metabolism is characterized by fuel monodependence, high-energy expenditure,
autonomy from the rest of body, local recycling, and marked division of labor between cell …
autonomy from the rest of body, local recycling, and marked division of labor between cell …
Remyelination after spinal cord injury: is it a target for repair?
After spinal cord injury (SCI) there is prolonged and dispersed oligodendrocyte cell death
that is responsible for widespread demyelination. To regenerate this lost myelin, many …
that is responsible for widespread demyelination. To regenerate this lost myelin, many …
N-Acetylaspartate reductions in brain injury: impact on post-injury neuroenergetics, lipid synthesis, and protein acetylation
JR Moffett, P Arun, PS Ariyannur… - Frontiers in …, 2013 - frontiersin.org
N-Acetylaspartate (NAA) is employed as a non-invasive marker for neuronal health using
proton magnetic resonance spectroscopy (MRS). This utility is afforded by the fact that NAA …
proton magnetic resonance spectroscopy (MRS). This utility is afforded by the fact that NAA …
Functional MRS studies of GABA and glutamate/Glx–A systematic review and meta-analysis
Functional magnetic resonance spectroscopy (fMRS) can be used to investigate
neurometabolic responses to external stimuli in-vivo, but findings are inconsistent. We …
neurometabolic responses to external stimuli in-vivo, but findings are inconsistent. We …
In vivo imaging of neuroinflammation in schizophrenia
In recent years evidence has accumulated to suggest that neuroinflammation might be an
early pathology of schizophrenia that later leads to neurodegeneration, yet the exact role in …
early pathology of schizophrenia that later leads to neurodegeneration, yet the exact role in …
Astrocytes as master modulators of neural networks: Synaptic functions and disease‐associated dysfunction of astrocytes
JA Stogsdill, CC Harwell… - Annals of the New York …, 2023 - Wiley Online Library
Astrocytes are the most abundant glial cell type in the central nervous system and are
essential to the development, plasticity, and maintenance of neural circuits. Astrocytes are …
essential to the development, plasticity, and maintenance of neural circuits. Astrocytes are …
Demyelination as a rational therapeutic target for ischemic or traumatic brain injury
Previous research on stroke and traumatic brain injury (TBI) heavily emphasized
pathological alterations in neuronal cells within gray matter. However, recent studies have …
pathological alterations in neuronal cells within gray matter. However, recent studies have …