Sepsis-associated encephalopathy (SAE) is a diffuse brain dysfunction that occurs
secondary to infection in the body without overt CNS infection. SAE is frequently …

The nervous and immune systems have evolved in parallel from the early bilaterians, in
which innate immunity and a central nervous system (CNS) coexisted for the first time, to …

Autophagy, a cellular process for organelle and protein turnover, regulates innate immune
responses. Here we demonstrate that depletion of the autophagic proteins LC3B and beclin …

Sepsis-associated acute kidney injury (AKI) is a common and morbid condition that is
distinguishable from typical ischemic renal injury by its paucity of tubular cell death. The …

Background Out of the myriad of complications associated with septic shock, septic-
associated encephalopathy (SAE) carries a significant risk of morbidity and mortality. Blood …

It is usually considered that larger brains have larger neurons, which consume more energy
individually, and are therefore accompanied by a larger number of glial cells per neuron …

Mitochondria play a vital role in maintaining cellular energy homeostasis, regulating
apoptosis, and controlling redox signaling. Dysfunction of mitochondria has been implicated …

Sepsis is often complicated by an acute and reversible deterioration of mental status, which
is associated with increased mortality and is consistent with delirium but can also be …

Sepsis is a leading cause of intensive care unit admission and death worldwide. Most
surviving patients show acute or chronic mental disorders, which are known as sepsis …

Abnormality in mitochondria has been suggested to be associated with development of
allergic airway disorders. In this study, to evaluate the relationship between mitochondrial …