Living organisms fabricate biomacromolecules such as DNA, RNA, and proteins by the self-
assembly process. The research on the mechanism of biomacromolecule formation also …

In the last few decades, we have witnessed the great advances of molecular self-assembly
in biomedical applications. Among the building blocks for molecular self-assembly, peptide …

Proteolysis targeting chimera (PROTAC) is an emerging pharmacological modality with
innovated post‐translational protein degradation capabilities. However, off‐target induced …

Materialomics integrates experiment, theory, and computation in a high‐throughput manner,
and has changed the paradigm for the research and development of new functional …

Anthocyanin, a unique natural polyphenol, is abundant in plants and widely utilized in
biomedicine, cosmetics, and the food industry due to its excellent antioxidant, anticancer …

Nanoarchitectures with promising properties have now been formed from many important
biomolecules. However, the preparation of nanoparticles of vitamin B12 and its derivatives …

Osteoporosis is primarily driven by an imbalance between bone resorption and formation,
stemming from enhanced osteoclast activity during bone remodeling. At the crux of this …

Osteosarcoma is an aggressive malignant tumor that primarily develops in children and
adolescents. The conventional treatments for osteosarcoma often exert negative effects on …

1BB as a co-stimulatory receptor represents a next-generation therapeutic target in immune-
oncology, which has been targeted by agonist antibodies or embedded in CAR-T cell …

Liver fibrosis is a process of excessive accumulation of extracellular matrix caused by liver
injury. Liver fibrosis can progress to cirrhosis or even liver cancer without proper …