Alzheimer's disease (AD) is a typical progressive, chronic neurodegenerative disorder with
worldwide prevalence. Its clinical manifestation involves the presence of extracellular …

Alzheimer's disease (AD) is the most common form of dementia, an eversible, progressive
disease that causes problems with memory, thinking, language, planning, and behavior …

Drosophila melanogaster has become a significant model organism for alcohol research. In
flies, a rich variety of behaviors can be leveraged for identifying genes affecting alcohol …

Background Molecular and behavioral studies support a role for innate immune
proinflammatory pathways in mediating the effects of alcohol. Increased levels of Toll‐like …

Transcriptome profiling enables discovery of gene networks that are altered in alcoholic
brains. This technique has revealed involvement of the brain's neuroimmune system in …

An understanding of neuroimmune signaling has become central to a description of how
alcohol causes addiction and how it damages people with an AUD. It is well known that the …

Our understanding of the networks of genes and protein functions involved in Alcohol Use
Disorder (AUD) remains incomplete, as do the mechanisms by which these networks lead to …

Environmental changes typically cause rapid gene expression responses in the exposed
organisms, including changes in the representation of gene isoforms with different functions …

Repeated exposure to alcohol alters neuromolecular signaling that influences acute and
long-lasting behaviors underlying Alcohol Use Disorder (AUD). Recent animal model …

NF-κB proteins are well known as transcription factors important in immune system
activation. In this highly conserved role, they contribute to changes in behavior in response …