Hot topics in allergen immunotherapy, 2023: current status and future perspective

M Zemelka‐Wiacek, I Agache, CA Akdis, M Akdis… - Allergy, 2024 - Wiley Online Library
The importance of allergen immunotherapy (AIT) is multifaceted, encompassing both clinical
and quality‐of‐life improvements and cost‐effectiveness in the long term. Key mechanisms …

Fungal exposome, human health, and unmet needs: a 2022 update with special focus on allergy

J Vitte, M Michel, A Malinovschi, M Caminati… - Allergy, 2022 - Wiley Online Library
Humans inhale, ingest, and touch thousands of fungi each day. The ubiquity and diversity of
the fungal kingdom, reflected by its complex taxonomy, are in sharp contrast with our scarce …

The CAR-HEMATOTOX score as a prognostic model of toxicity and response in patients receiving BCMA-directed CAR-T for relapsed/refractory multiple myeloma

K Rejeski, DK Hansen, R Bansal, P Sesques… - Journal of Hematology & …, 2023 - Springer
Abstract Background BCMA-directed CAR T-cell therapy (CAR-T) has altered the treatment
landscape of relapsed/refractory (r/r) multiple myeloma, but is hampered by unique side …

EAACI guidelines on environmental science in allergic diseases and asthma–leveraging artificial intelligence and machine learning to develop a causality model in …

MH Shamji, M Ollert, IM Adcock, O Bennett, A Favaro… - Allergy, 2023 - Wiley Online Library
Allergic diseases and asthma are intrinsically linked to the environment we live in and to
patterns of exposure. The integrated approach to understanding the effects of exposures on …

Childhood asthma phenotypes and endotypes: a glance into the mosaic

F Foppiano, B Schaub - Molecular and Cellular Pediatrics, 2023 - Springer
Background Asthma is an inflammatory lung disease that constitutes the most common
noncommunicable chronic disease in childhood. Childhood asthma shows large …

Allergen immunotherapy for asthma

JH Kappen, I Agache, M Jutel, P Pillai… - The Journal of Allergy …, 2024 - Elsevier
Allergen immunotherapy is a disease-modifying treatment for IgE-mediated allergies
reducing disease burden and symptoms in patients with allergic rhinitis, with or without …

Patient‐centered digital biomarkers for allergic respiratory diseases and asthma: The ARIA‐EAACI approach–ARIA‐EAACI Task Force Report

J Bousquet, MH Shamji, JM Anto, HJ Schünemann… - Allergy, 2023 - Wiley Online Library
Biomarkers for the diagnosis, treatment and follow‐up of patients with rhinitis and/or asthma
are urgently needed. Although some biologic biomarkers exist in specialist care for asthma …

Current state and prospects of artificial intelligence in allergy

M van Breugel, RSN Fehrmann, M Bügel, FI Rezwan… - Allergy, 2023 - Wiley Online Library
The field of medicine is witnessing an exponential growth of interest in artificial intelligence
(AI), which enables new research questions and the analysis of larger and new types of …

[HTML][HTML] Immune-mediated disease caused by climate change-associated environmental hazards: mitigation and adaptation

I Agache, C Akdis, M Akdis, A Al-Hemoud… - Frontiers in …, 2024 - frontiersin.org
Global warming and climate change have increased the pollen burden and the frequency
and intensity of wildfires, sand and dust storms, thunderstorms, and heatwaves—with …

Advances in the relationship between respiratory viruses and asthma

SJ Romero-Tapia, CG Guzmán Priego… - Journal of Clinical …, 2023 - mdpi.com
Several studies have reported that viral infection is closely associated with the onset,
progression, and exacerbation of asthma. The purpose of this review is to summarize the …