PLGA's plight and the role of stealth surface modification strategies in its use for intravenous particulate drug delivery
VV Sheffey, EB Siew, EEL Tanner… - Advanced …, 2022 - Wiley Online Library
Numerous human disorders can benefit from targeted, intravenous (IV) drug delivery.
Polymeric nanoparticles have been designed to undergo systemic circulation and deliver …
Polymeric nanoparticles have been designed to undergo systemic circulation and deliver …
Pharmacokinetic, pharmacodynamic and biodistribution following oral administration of nanocarriers containing peptide and protein drugs
The influence of nanoparticle (NP) formulations on the pharmacokinetic, pharmacodynamic
and biodistribution profiles of peptide-and protein-like drugs following oral administration is …
and biodistribution profiles of peptide-and protein-like drugs following oral administration is …
Lipid-PLGA hybrid nanoparticles of paclitaxel: Preparation, characterization, in vitro and in vivo evaluation
Paclitaxel loaded lipid-polymer nanoparticles (NPs) were successfully synthesized using
poly lactide-co-glycolide (PLGA) as polymer and stearyl amine, soya lecithin as lipids via …
poly lactide-co-glycolide (PLGA) as polymer and stearyl amine, soya lecithin as lipids via …
Co-delivery of etoposide and cisplatin in dual-drug loaded nanoparticles synergistically improves chemoradiotherapy in non-small cell lung cancer models
M Zhang, CT Hagan IV, H Foley, X Tian, F Yang… - Acta biomaterialia, 2021 - Elsevier
Chemoradiotherapy with cisplatin and etoposide is a curative management regimen for both
small and non-small cell lung cancers. While the treatment regimen is effective, it also has a …
small and non-small cell lung cancers. While the treatment regimen is effective, it also has a …
Nanoparticle co-delivery of wortmannin and cisplatin synergistically enhances chemoradiotherapy and reverses platinum resistance in ovarian cancer models
Most ovarian cancer patients respond well to initial platinum-based chemotherapy.
However, within a year, many patients experience disease recurrence with a platinum …
However, within a year, many patients experience disease recurrence with a platinum …
Development of solid lipid nanoparticles (SLNs) of lopinavir using hot self nano-emulsification (SNE) technique
JS Negi, P Chattopadhyay, AK Sharma… - European Journal of …, 2013 - Elsevier
Solid lipid nanoparticles (SLNs) of poor orally bioavailable drug lopinavir were prepared
using hot self nano-emulsification (SNE) technique. Hot isotropic mixture of stearic acid …
using hot self nano-emulsification (SNE) technique. Hot isotropic mixture of stearic acid …
[HTML][HTML] Influence of surface charge on the in vitro protein adsorption and cell cytotoxicity of paclitaxel loaded poly (ε-caprolactone) nanoparticles
The biokinetic fate of polymeric nanoparticles in the physiological milieu is strongly
influenced by its properties such as size, surface charge and surface affinity. The …
influenced by its properties such as size, surface charge and surface affinity. The …
Poloxamers for surface modification of hydrophobic drug carriers and their effects on drug delivery
QTH Shubhra, J Tóth, J Gyenis, T Feczkó - Polymer Reviews, 2014 - Taylor & Francis
Tri-block copolymer poloxamers are successfully employed for reducing adsorption of
proteinous molecules onto hydrophobic surfaces which will protect them from quick …
proteinous molecules onto hydrophobic surfaces which will protect them from quick …
New potential strategies for Alzheimer's disease prevention: pegylated biodegradable dexibuprofen nanospheres administration to APPswe/PS1dE9
E Sánchez-López, M Ettcheto, MA Egea… - … , Biology and Medicine, 2017 - Elsevier
Dexibuprofen loaded pegylated poly (lactic-co-glycolic) nanospheres prepared by solvent
diffusion method were designed to increase Dexibuprofen brain delivery reducing systemic …
diffusion method were designed to increase Dexibuprofen brain delivery reducing systemic …
Brain-targeted, drug-loaded solid lipid nanoparticles against glioblastoma cells in culture
G Ak, A Ünal, T Karakayalı, B Özel, NS Günel… - Colloids and Surfaces B …, 2021 - Elsevier
The aim of this study was the preparation of solid lipid nanoparticles (SLN) formed from cetyl
palmitate with having targeting molecules for monocarboxylate transporter-1 (MCT-1): β …
palmitate with having targeting molecules for monocarboxylate transporter-1 (MCT-1): β …