Men and women respond differently to antipsychotic drugs

MV Seeman - Neuropharmacology, 2020 - Elsevier
Background Because women are often perceived as having better outcomes than men in
psychotic illnesses such as schizophrenia–women are less often in hospital, have a lower …

Mortality, revascularization, and cardioprotective pharmacotherapy after acute coronary syndrome in patients with severe mental illness: a systematic review and meta …

JKN Chan, RST Chu, C Hung, JWY Law… - Schizophrenia …, 2022 - academic.oup.com
Abstract Background and Hypothesis People with severe mental illness (SMI) may
experience excess mortality and inequitable treatment following acute coronary syndrome …

Factors influencing harmonized health data collection, sharing and linkage in Denmark and Switzerland: a systematic review

LD Geneviève, A Martani, MC Mallet, T Wangmo… - PloS one, 2019 - journals.plos.org
Introduction The digitalization of medicine has led to a considerable growth of
heterogeneous health datasets, which could improve healthcare research if integrated into …

Clozapine blood concentration predicts corrected QT-interval prolongation in patients with psychoses

K Kim, YS Kim, E Joo, E Kim, S Bhang… - Journal of Clinical …, 2022 - journals.lww.com
Background Corrected QT-interval (QTc) prolongation (QTP) is a rare but fatal adverse effect
of antipsychotics. Clozapine is the only antipsychotic recommended for treatment of resistant …

Antipsychotic polypharmacy-related cardiovascular morbidity and mortality: a comprehensive review

AN Edinoff, ED Ellis, LM Nussdorf, TW Hill… - Neurology …, 2022 - mdpi.com
Schizophrenia is a psychotic disorder that exists at the more extreme end of a spectrum of
diseases, and significantly affects daily functioning. Cardiovascular adverse effects of …

Do we need sex-oriented clinical practice guidelines for the treatment of schizophrenia?

P Fernando, IEC Sommer, A Hasan - Current opinion in …, 2020 - journals.lww.com
Sex-specific aspects can already be integrated in clinical guideline recommendations,
especially with regard to efficacy and tolerability of antipsychotic treatment. Moreover, these …

Drug use and torsades de pointes cardiac arrhythmias in Sweden: a nationwide register-based cohort study

B Danielsson, J Collin, A Nyman, A Bergendal… - BMJ open, 2020 - bmjopen.bmj.com
Objective To study the occurrence of torsades de pointes (TdP) ventricular tachycardia in
relation to use of drugs labelled with TdP risk, using two nationwide Swedish registers …

Comparison of frontal QRS-T angle in patients with schizophrenia and healthy volunteers

A Tekin, Z Tanrıverdi, Y Kapıcı, B Güc… - Journal of Psychiatric …, 2022 - Elsevier
Cardiovascular diseases are the most prominent cause of death in patients with
schizophrenia. Frontal QRS-T (fQRS-T) angle is a novel marker of myocardial depolarization …

QTc prolongation in patients with schizophrenia taking antipsychotics: Prevalence and risk factors

W Du, MW Ge, FH Hu, YJ Jia, DY Zhao… - Journal of …, 2023 - journals.sagepub.com
Background: QTc prolongation is one of the possible complications in patients with
schizophrenia taking antipsychotics, which leads to malignant cardiac arrhythmia. No meta …

Pharmacodynamic Drug–Drug interactions of QT-prolonging drugs in hospitalized psychiatric patients

G Hefner, M Hahn, C Hiemke, S Toto, J Wolff… - Journal of Neural …, 2021 - Springer
At least 170 approved drugs are linked to QT prolongation, which can lead to serious
adverse drug reactions (ADRs), such as Torsade de Pointes (TdP). The aim of this study was …