The therapeutic potential of natural dietary flavonoids against SARS-CoV-2 infection

Z Wang, L Yang - Nutrients, 2023 - mdpi.com
The exploration of non-toxic and cost-effective dietary components, such as epigallocatechin
3-gallate and myricetin, for health improvement and disease treatment has recently attracted …

Epigallocatechin gallate: Phytochemistry, bioavailability, utilization challenges, and strategies

S Mehmood, M Maqsood, N Mahtab… - Journal of Food …, 2022 - Wiley Online Library
Epigallocatechin gallate (EGCG), a green tea catechin, has gained the attention of current
study due to its excellent health‐promoting effects. It possesses anti‐obesity, antimicrobial …

[HTML][HTML] SARS-CoV-2 neutralizing activity of polyphenols in a special green tea extract preparation

E Kicker, G Tittel, T Schaller, EM Pferschy-Wenzig… - Phytomedicine, 2022 - Elsevier
Background The COVID-19 pandemic will continue to threaten our health care systems in
the next years. In addition to vaccination there is a need for effective tools for prevention and …

[HTML][HTML] Therapeutic potential of green tea catechin,(-)-epigallocatechin-3-O-gallate (EGCG) in SARS-CoV-2 infection: Major interactions with host/virus proteases

B Dinda, S Dinda, M Dinda - Phytomedicine Plus, 2023 - Elsevier
Background The current COVID-19 pandemic from the human pathogenic virus SARS-CoV-
2 has resulted in a major health hazard globally. The morbidity and transmission modality of …

Effects of tea, catechins and catechin derivatives on Omicron subvariants of SARS-CoV-2

M Shin-Ya, M Nakashio, E Ohgitani, A Suganami… - Scientific Reports, 2023 - nature.com
The Omicron subvariants of SARS-CoV-2 have multiple mutations in the S-proteins and
show high transmissibility. We previously reported that tea catechin (−)-epigallocatechin …

Kyasanur Forest disease virus NS3 helicase: Insights into structure, activity, and inhibitors

C Zhang, Y Li, A Samad, H He, H Ma, Y Chen… - International Journal of …, 2024 - Elsevier
Kyasanur Forest disease virus (KFDV), a tick-borne flavivirus prevalent in India, presents a
serious threat to human health. KFDV NS3 helicase (NS3hel) is considered a potential drug …

Potential of green tea EGCG in neutralizing SARS-CoV-2 Omicron variant with greater tropism toward the upper respiratory tract

Z Zhang, M Hao, X Zhang, Y He, X Chen… - Trends in Food Science …, 2023 - Elsevier
Background COVID-19 due to SARS-CoV-2 infection has had an enormous adverse impact
on global public health. As the COVID-19 pandemic evolves, the WHO declared several …

Epigallocatechin-3-gallate ameliorates inflammatory injury caused by sepsis by regulating the lncRNA PVT1/miR-16-5p/TLR4 axis

W Yuan, S Li, YN Yang, H Gao, C Liu - Cytokine, 2023 - Elsevier
Background Sepsis is identified as a severe inflammatory disease. Epigallocatechin-3-
gallate (EGCG) has been reported to be a powerful anti-inflammatory chemical substance in …

Plant-Derived Epi-Nutraceuticals as Potential Broad-Spectrum Anti-Viral Agents

R Gabbianelli, E Shahar, G De Simone, C Rucci… - Nutrients, 2023 - mdpi.com
Although the COVID-19 pandemic appears to be diminishing, the emergence of SARS-CoV-
2 variants represents a threat to humans due to their inherent transmissibility, immunological …

Molecular mechanisms of possible action of phenolic compounds in COVID-19 protection and prevention

N Gligorijevic, M Radomirovic, O Nedic… - International Journal of …, 2021 - mdpi.com
The worldwide outbreak of COVID-19 was caused by a pathogenic virus called Severe
Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). Therapies against SARS-CoV-2 …