[HTML][HTML] Human Stem Cells for Cardiac Disease Modeling and Preclinical and Clinical Applications—Are We on the Road to Success?
CD Correia, A Ferreira, MT Fernandes, BM Silva… - Cells, 2023 - mdpi.com
Cardiovascular diseases (CVDs) are pointed out by the World Health Organization (WHO)
as the leading cause of death, contributing to a significant and growing global health and …
as the leading cause of death, contributing to a significant and growing global health and …
[HTML][HTML] Healing the broken heart; the immunomodulatory effects of stem cell therapy
MJ Wagner, M Khan, S Mohsin - Frontiers in Immunology, 2020 - frontiersin.org
Cardiovascular Disease (CVD) is a leading cause of mortality within the United States.
Current treatments being administered to patients who suffered a myocardial infarction (MI) …
Current treatments being administered to patients who suffered a myocardial infarction (MI) …
Expansion and characterization of neonatal cardiac pericytes provides a novel cellular option for tissue engineering in congenital heart disease
E Avolio, I Rodriguez‐Arabaolaza… - Journal of the …, 2015 - Am Heart Assoc
Background Living grafts produced by combining autologous heart‐resident stem/progenitor
cells and tissue engineering could provide a new therapeutic option for definitive correction …
cells and tissue engineering could provide a new therapeutic option for definitive correction …
Mesenchymal stem cells preserve neonatal right ventricular function in a porcine model of pressure overload
Limited therapies exist for patients with congenital heart disease (CHD) who develop right
ventricular (RV) dysfunction. Bone marrow-derived mesenchymal stem cells (MSCs) have …
ventricular (RV) dysfunction. Bone marrow-derived mesenchymal stem cells (MSCs) have …
Study design and rationale for ELPIS: A phase I/IIb randomized pilot study of allogeneic human mesenchymal stem cell injection in patients with hypoplastic left heart …
S Kaushal, B Wehman, N Pietris, C Naughton… - American heart …, 2017 - Elsevier
Despite advances in surgical technique and postoperative care, long-term survival of
children born with hypoplastic left heart syndrome (HLHS) remains limited, with cardiac …
children born with hypoplastic left heart syndrome (HLHS) remains limited, with cardiac …
[PDF][PDF] Comparative efficacy and mechanism of action of cardiac progenitor cells after cardiac injury
Successful cell therapy requires cells to resist the hostile ischemic myocardium, be retained
to continue secreting cardioprotective growth factors/exosomes, and resist immunological …
to continue secreting cardioprotective growth factors/exosomes, and resist immunological …
[HTML][HTML] Amniotic fluid mesenchymal stromal cells derived from fetuses with isolated cardiac defects exhibit decreased proliferation and cardiomyogenic potential
M Jain, N Singh, R Fatima, A Nachanekar, M Pradhan… - Biology, 2023 - mdpi.com
Simple Summary Congenital heart defect (CHD) is the most common birth defect that affects
the structure of the heart from birth. A possible reason for this occurrence could be …
the structure of the heart from birth. A possible reason for this occurrence could be …
Cell therapy trials in congenital heart disease
H Oh - Circulation research, 2017 - Am Heart Assoc
Dramatic evolution in medical and catheter interventions and complex surgeries to treat
children with congenital heart disease (CHD) has led to a growing number of patients with a …
children with congenital heart disease (CHD) has led to a growing number of patients with a …
In Vitro and In Vivo Preclinical Testing of Pericyte‐Engineered Grafts for the Correction of Congenital Heart Defects
VV Alvino, M Kilcooley, AC Thomas… - Journal of the …, 2020 - Am Heart Assoc
Background We have previously reported the possibility of using pericytes from leftovers of
palliative surgery of congenital heart disease to engineer clinically certified prosthetic grafts …
palliative surgery of congenital heart disease to engineer clinically certified prosthetic grafts …
[HTML][HTML] Establishment of a protocol to administer immunosuppressive drugs for iPS cell-derived cardiomyocyte patch transplantation in a rat myocardial infarction …
E Ito, A Kawamura, T Kawamura, M Takeda… - Scientific Reports, 2023 - nature.com
Transplantation of human allogeneic induced pluripotent stem cell-derived cardiomyocytes
(hiPSC-CMs) is a new, promising treatment for severe heart failure. However …
(hiPSC-CMs) is a new, promising treatment for severe heart failure. However …