Combined Second Harmonic Generation and Fluorescence Analyses of the Structures and Dynamics of Molecules on Lipids Using Dual-Probes: A Review

Y Hou, J Li, B Li, Q Yuan, W Gan - Molecules, 2022 - mdpi.com
Revealing the structures and dynamic behaviors of molecules on lipids is crucial for
understanding the mechanism behind the biophysical processes, such as the preparation …

On the models for understanding the second harmonic generation scattering from lipid membranes and the corresponding molecular kinetics

S Chen, Y Hou, B Xu, S Chen, Q Yuan… - Colloids and Surfaces A …, 2024 - Elsevier
The kinetics of molecular transportation through lipid membranes are key information for
understanding many biophysical processes in real cells or protocells. Second harmonic …

Determination of bacterial surface charge density via saturation of adsorbed ions

MJ Wilhelm, MS Gh, T Wu, Y Li, CM Chang, J Ma… - Biophysical …, 2021 - cell.com
Bacterial surface charge is a critical characteristic of the cell's interfacial physiology that
influences how the cell interacts with the local environment. A direct, sensitive, and accurate …

Indole facilitates antimicrobial uptake in bacteria

T Wu, MJ Wilhelm, Y Li, J Ma, HL Dai - ACS Infectious Diseases, 2022 - ACS Publications
Indole signaling in bacteria plays an important role in antibiotic resistance, persistence, and
tolerance. Here, we used the nonlinear optical technique, second-harmonic light scattering …

Unveiling the molecular dynamics in a living cell to the subcellular organelle level using second-harmonic generation spectroscopy and microscopy

B Li, J Li, W Gan, Y Tan, Q Yuan - Analytical Chemistry, 2021 - ACS Publications
Second-harmonic generation (SHG) microscopy has been proved to be a powerful method
for investigating the structures of biomaterials. SHG spectra were also generally used to …

A NIR-activated and mild-temperature-sensitive nanoplatform with an HSP90 inhibitor for combinatory chemotherapy and mild photothermal therapy in cancel cells

Y Peng, H Jiang, B Li, Y Liu, B Guo, W Gan - Pharmaceutics, 2023 - mdpi.com
Mild photothermal therapy (PTT) shows great potential to treat cancers while avoiding
unwanted damage to surrounding normal cells. However, the efficacy of mild PTT is …

AIEgens for dual second harmonic generation and fluorescence “turn-on” imaging of membrane and photodynamic therapy in cancer cells

Y Peng, Y Yan, P Li, B Li, H Jiang, B Guo… - Materials Chemistry …, 2023 - pubs.rsc.org
The integration of second harmonic generation (SHG) microscopic imaging and aggregation-
induced emission fluorescence imaging would greatly boost the imaging outcomes because …

Optical spectroscopy of surfaces, interfaces, and thin films

TJ Blackburn, SM Tyler, JE Pemberton - Analytical Chemistry, 2022 - ACS Publications
Efforts to characterize solid/liquid, solid/gas, liquid/gas, liquid/liquid, and liquid/gas
interfaces utilizing optical spectroscopies in the ultraviolet− visible (UV− vis), infrared (IR) …

Revealing the mechanisms of vesicle formation with multiple spectral methods

J Li, SL Chen, Y Hou, Q Yuan, W Gan - Physical Chemistry Chemical …, 2022 - pubs.rsc.org
The investigation of the self-assembly of amphiphilic molecules and the formation of
micelles/vesicles has attracted significant attention. However, in situ and real-time methods …

The effect of side group on the dynamic behavior of anthracyclines on DOPG lipid membranes revealed by second harmonic generation and fluorescence

Y Hou, J Li, XX Liu, Y Ruan, S Chen, Q Yuan, W Gan - Chemical Physics, 2021 - Elsevier
In this work we use two-photon fluorescence (TPF) and surface-sensitive second harmonic
generation (SHG) techniques to investigate the interaction of the lipid membrane with …