The light sensor of vertebrate scotopic (low-light) vision, rhodopsin, is a G-protein-coupled
receptor comprising a polypeptide chain with bound chromophore, 11-cis-retinal, that …

There is an urgency to find new treatment strategies that could prevent or delay the onset or
progression of AMD. Different classes of lipids and lipoproteins metabolism genes have …

The retinal pigment epithelium-photoreceptor interphase is renewed each day in a stunning
display of cellular interdependence. While photoreceptors use photosensitive pigments to …

To serve vision, vertebrate rod and cone photoreceptors must detect photons, convert the
light stimuli into cellular signals, and then convey the encoded information to downstream …

Omega‐3 (ω‐3) fatty acids (FA s) such as docosahexaenoic acid (DHA) and
eicosapentaenoic acid (EPA) are known to have important roles in human health and …

The primary cilium is a ubiquitous microtubule-based organelle that senses external
environment and modulates diverse signaling pathways in different cell types and tissues …

Cilia are hair-like projections found on almost all cells in the human body. Originally
believed to function merely in motility, the function of solitary non-motile (primary) cilia was …

The primary cilium is a highly conserved organelle housing specialized molecules
responsible for receiving and processing extracellular signals. A recently discovered …

Eye photoreceptor membrane discs in outer rod segments are highly enriched in the visual
pigment rhodopsin and the ω-3 fatty acid docosahexaenoic acid (DHA). The eye acquires …

Cold stimulation dynamically remodels mitochondria in brown adipose tissue (BAT) to
facilitate non-shivering thermogenesis in mammals, but what regulates mitochondrial …