[HTML][HTML] Targeted therapy for hepatocellular carcinoma

A Huang, XR Yang, WY Chung, AR Dennison… - Signal transduction and …, 2020 - nature.com
The last 3 years have seen the emergence of promising targeted therapies for the treatment
of hepatocellular carcinoma (HCC). Sorafenib has been the mainstay of treatment for a …

Challenges in liver cancer and possible treatment approaches

D Anwanwan, SK Singh, S Singh, V Saikam… - Biochimica et Biophysica …, 2020 - Elsevier
Globally, liver cancer is the most frequent fatal malignancy; in the United States, it ranks fifth.
Patients are often diagnosed with liver cancer in advanced stages, contributing to its poor …

Transarterial chemoembolization plus lenvatinib versus transarterial chemoembolization plus sorafenib as first‐line treatment for hepatocellular carcinoma with portal …

X Ding, W Sun, W Li, Y Shen, X Guo, Y Teng, X Liu… - Cancer, 2021 - Wiley Online Library
BACKGROUND The efficacy and safety of transarterial chemoembolization (TACE) plus
lenvatinib in patients with hepatocellular carcinoma (HCC) and portal vein tumor thrombus …

[HTML][HTML] Transarterial chemoembolization in hepatocellular carcinoma treatment: Barcelona clinic liver cancer staging system

K Han, JH Kim - World journal of gastroenterology: WJG, 2015 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC), the fifth most common cancer that predominantly occurs in
liver cirrhosis patients, requires staging systems to design treatments. The barcelona clinic …

[HTML][HTML] Transarterial chemoembolization combined with lenvatinib plus PD-1 inhibitor for advanced hepatocellular carcinoma: a retrospective cohort study

M Cai, W Huang, J Huang, W Shi, Y Guo… - Frontiers in …, 2022 - frontiersin.org
Purpose To investigate the efficacy and safety of transarterial chemoembolization (TACE)
combined with lenvatinib plus PD-1 inhibitor (TACE-LP) versus TACE combined with …

[HTML][HTML] Propensity score matching: a conceptual review for radiology researchers

S Baek, SH Park, E Won, YR Park… - Korean journal of …, 2015 - synapse.koreamed.org
The propensity score is defined as the probability of each individual study subject being
assigned to a group of interest for comparison purposes. Propensity score adjustment is a …

The impact of tumor size on long-term survival outcomes after resection of solitary hepatocellular carcinoma: single-institution experience with 2558 patients

S Hwang, YJ Lee, KH Kim, CS Ahn, DB Moon… - Journal of …, 2015 - Elsevier
Background According to the 7th AJCC TNM staging system, solitary hepatocellular
carcinoma (HCC) is classified as T1 or T2 based on microvascular invasion (MVI) regardless …

Role of locoregional therapies in the wake of systemic therapy

DH Palmer, K Malagari, LM Kulik - Journal of hepatology, 2020 - Elsevier
Multiple systemic agents have recently been approved in the first-and second-line setting for
hepatocellular carcinoma (HCC), increasing the therapeutic options for patients and treating …

[HTML][HTML] TACE plus lenvatinib versus TACE plus sorafenib for unresectable hepatocellular carcinoma with portal vein tumor thrombus: a prospective cohort study

B Yang, L Jie, T Yang, M Chen, Y Gao, T Zhang… - Frontiers in …, 2021 - frontiersin.org
Background and Objectives This study aimed to compare the efficacy of transarterial
chemoembolization (TACE) plus sorafenib (TACE-S) to TACE plus lenvatinib (TACE-L) for …

[HTML][HTML] Overall survival in response to sorafenib versus radiotherapy in unresectable hepatocellular carcinoma with major portal vein tumor thrombosis: propensity …

T Nakazawa, H Hidaka, A Shibuya, Y Okuwaki… - BMC …, 2014 - Springer
Background This study investigated the survival benefits of sorafenib vs. radiotherapy (RT)
in patients with unresectable hepatocellular carcinoma (HCC) and portal vein tumor …