Non-steroidal anti-inflammatory drugs (NSAIDs) and organ damage: A current perspective

S Bindu, S Mazumder, U Bandyopadhyay - Biochemical pharmacology, 2020 - Elsevier
Owing to the efficacy in reducing pain and inflammation, non-steroidal anti-inflammatory
drugs (NSAIDs) are amongst the most popularly used medicines confirming their position in …

Non-steroidal anti-inflammatory drugs (NSAIDs): A current insight into its molecular mechanism eliciting organ toxicities

NK Panchal, EP Sabina - Food and Chemical Toxicology, 2023 - Elsevier
Non-steroidal anti-inflammatory drugs (NSAIDs) are a class of medications that are routinely
been used across the world. Their analgesic, anti-inflammatory, and antipyretic effects have …

Biomarkers of oxidative stress tethered to cardiovascular diseases

P Panda, HK Verma, S Lakkakula… - Oxidative Medicine …, 2022 - Wiley Online Library
Cardiovascular disease (CVD) is a broad term that incorporated a group of conditions that
affect the blood vessels and the heart. CVD is a foremost cause of fatalities around the …

Cardiovascular effects of approved drugs for rheumatoid arthritis

F Atzeni, J Rodríguez-Carrio, CD Popa… - Nature Reviews …, 2021 - nature.com
The risk of cardiovascular disease is increased in patients with rheumatoid arthritis
compared with the general population owing to the influence of traditional and non …

NSAID induced gastrointestinal damage and designing GI-sparing NSAIDs

G García-Rayado, M Navarro… - Expert review of clinical …, 2018 - Taylor & Francis
NSAIDs are widely used to treat pain and rheumatic conditions, but they induce adverse
events in different body systems, although the major, most frequent events occur in the …

The role of flavonoids in autoimmune diseases: Therapeutic updates

KRR Rengasamy, H Khan, S Gowrishankar… - Pharmacology & …, 2019 - Elsevier
Flavonoids are natural polyphenolic compounds which are included in a panoply of drugs
and used to treat and/or manage human ailments such as metabolic, cardiovascular …

Inflammatory bowel disease: tri-directional relationship between microbiota, immune system and intestinal epithelium

S Ahlawat, P Kumar, H Mohan, S Goyal… - Critical Reviews in …, 2021 - Taylor & Francis
Human gut microbiota contributes to host nutrition and metabolism, sustains intestinal cell
proliferation and differentiation, and modulates host immune system. The alterations in their …

[HTML][HTML] The regulation of the TLR4/NF-κB and Nrf2/HO-1 signaling pathways is involved in the inhibition of lipopolysaccharide-induced inflammation and oxidative …

C Park, HJ Cha, H Lee, GY Kim, YH Choi - Archives of Biochemistry and …, 2021 - Elsevier
Morroniside, a major iridoid glycoside isolated from Cornus officinalis, has a variety of
beneficial pharmacological properties. Although morroniside has recently been reported to …

Celecoxib in cancer therapy and prevention–review

N Tołoczko-Iwaniuk… - Current Drug …, 2019 - ingentaconnect.com
Background and Objectives: It is generally accepted that inflammatory cells found in the
tumor microenvironment are involved in the neoplastic process, promoting cell proliferation …

Role of lipid mediators in the regulation of oxidative stress and inflammatory responses in dairy cattle

V Mavangira, LM Sordillo - Research in veterinary science, 2018 - Elsevier
Periparturient dairy cows experience an increased incidence and severity of several
inflammatory-based diseases such as mastitis and metritis. Factors associated with the …