As a phenolic acid compound, caffeic acid (CA) can be isolated from different sources such
as tea, wine and coffee. Caffeic acid phenethyl ester (CAPE) is naturally occurring derivative …

Triple-negative breast cancer (TNBC) is a subtype of human breast cancer with one of the
worst prognoses, with no targeted therapeutic strategies currently available. Regulated cell …

The definition for autophagy holds a 'single'meaning as a conserved cellular process that
constitutes a recycling pathway for damaged organelles and long-lived proteins to maintain …

Cancer is the second leading cause of death after cardiovascular diseases. Conventional
anticancer therapies are associated with lack of selectivity and serious side effects. Cancer …

Perineural invasion (PNI) is the process of neoplastic invasion of peripheral nerves and is
considered to be the fifth mode of cancer metastasis. PNI has been detected in head and …

As a devastating disease, breast cancer has been responsible for decrease in life
expectancy of females and its morbidity and mortality are high. Breast cancer is the most …

Gastric cancer (GC) is often diagnosed in the advanced stages with a poor prognosis.
Thymoquinone (TQ) is known for its antitumor activity; however, the specific mechanism in …

The variety of therapies available for treating and preventing triple-negative breast cancer
(TNBC) is constrained by the absence of progesterone receptors, estrogen receptors, and …

Prostate cancer (PC) and colon cancer significantly contribute to global cancer-related
morbidity and mortality. Thymoquinone (TQ), a naturally occurring phytochemical found in …

Tumor cells employ multiple signaling mediators to escape the hypoxic condition and trigger
angiogenesis and metastasis. As a critical orchestrate of tumorigenic conditions, hypoxia …