Caffeic acid and its derivatives as potential modulators of oncogenic molecular pathways: New hope in the fight against cancer
As a phenolic acid compound, caffeic acid (CA) can be isolated from different sources such
as tea, wine and coffee. Caffeic acid phenethyl ester (CAPE) is naturally occurring derivative …
as tea, wine and coffee. Caffeic acid phenethyl ester (CAPE) is naturally occurring derivative …
[HTML][HTML] Targeting regulated cell death (RCD) with small-molecule compounds in triple-negative breast cancer: a revisited perspective from molecular mechanisms to …
M Liao, R Qin, W Huang, HP Zhu, F Peng… - Journal of Hematology & …, 2022 - Springer
Triple-negative breast cancer (TNBC) is a subtype of human breast cancer with one of the
worst prognoses, with no targeted therapeutic strategies currently available. Regulated cell …
worst prognoses, with no targeted therapeutic strategies currently available. Regulated cell …
Beclin1-mediated interplay between autophagy and apoptosis: New understanding
K Prerna, VK Dubey - International journal of biological macromolecules, 2022 - Elsevier
The definition for autophagy holds a 'single'meaning as a conserved cellular process that
constitutes a recycling pathway for damaged organelles and long-lived proteins to maintain …
constitutes a recycling pathway for damaged organelles and long-lived proteins to maintain …
[HTML][HTML] Plants as a source of anticancer agents: From bench to bedside
Cancer is the second leading cause of death after cardiovascular diseases. Conventional
anticancer therapies are associated with lack of selectivity and serious side effects. Cancer …
anticancer therapies are associated with lack of selectivity and serious side effects. Cancer …
[HTML][HTML] Perineural invasion-associated biomarkers for tumor development
Q Liu, Z Ma, Q Cao, H Zhao, Y Guo, T Liu, J Li - Biomedicine & …, 2022 - Elsevier
Perineural invasion (PNI) is the process of neoplastic invasion of peripheral nerves and is
considered to be the fifth mode of cancer metastasis. PNI has been detected in head and …
considered to be the fifth mode of cancer metastasis. PNI has been detected in head and …
[HTML][HTML] Towards dual function of autophagy in breast cancer: A potent regulator of tumor progression and therapy response
M Hashemi, MDA Paskeh, S Orouei, P Abbasi… - Biomedicine & …, 2023 - Elsevier
As a devastating disease, breast cancer has been responsible for decrease in life
expectancy of females and its morbidity and mortality are high. Breast cancer is the most …
expectancy of females and its morbidity and mortality are high. Breast cancer is the most …
Thymoquinone induces apoptosis and protective autophagy in gastric cancer cells by inhibiting the PI3K/Akt/mTOR pathway
P He, Y He, J Ma, Y Liu, C Liu, Y Baoping… - Phytotherapy …, 2023 - Wiley Online Library
Gastric cancer (GC) is often diagnosed in the advanced stages with a poor prognosis.
Thymoquinone (TQ) is known for its antitumor activity; however, the specific mechanism in …
Thymoquinone (TQ) is known for its antitumor activity; however, the specific mechanism in …
[HTML][HTML] Anticancer effects of thymoquinone through the antioxidant activity, upregulation of Nrf2, and downregulation of PD-L1 in triple-negative breast cancer cells
GM Adinew, SS Messeha, E Taka, RB Badisa… - Nutrients, 2022 - mdpi.com
The variety of therapies available for treating and preventing triple-negative breast cancer
(TNBC) is constrained by the absence of progesterone receptors, estrogen receptors, and …
(TNBC) is constrained by the absence of progesterone receptors, estrogen receptors, and …
[HTML][HTML] Thymoquinone potentially modulates the expression of key onco-and tumor suppressor miRNAs in prostate and colon cancer cell lines: Insights from PC3 and …
SM Osorio-Pérez, C Estrada-Meza, LM Ruiz-Manriquez… - Genes, 2023 - mdpi.com
Prostate cancer (PC) and colon cancer significantly contribute to global cancer-related
morbidity and mortality. Thymoquinone (TQ), a naturally occurring phytochemical found in …
morbidity and mortality. Thymoquinone (TQ), a naturally occurring phytochemical found in …
Modulation of hypoxia-inducible factor-1 signaling pathways in cancer angiogenesis, invasion, and metastasis by natural compounds: a comprehensive and critical …
Tumor cells employ multiple signaling mediators to escape the hypoxic condition and trigger
angiogenesis and metastasis. As a critical orchestrate of tumorigenic conditions, hypoxia …
angiogenesis and metastasis. As a critical orchestrate of tumorigenic conditions, hypoxia …