Insights into N6-methyladenosine and programmed cell death in cancer
L Liu, H Li, D Hu, Y Wang, W Shao, J Zhong, S Yang… - Molecular Cancer, 2022 - Springer
Abstract N6-methyladenosine (m6A) methylation, the most common form of internal RNA
modification in eukaryotes, has gained increasing attention and become a hot research topic …
modification in eukaryotes, has gained increasing attention and become a hot research topic …
Mapping the epigenetic modifications of DNA and RNA
Over 17 and 160 types of chemical modifications have been identified in DNA and RNA,
respectively. The interest in understanding the various biological functions of DNA and RNA …
respectively. The interest in understanding the various biological functions of DNA and RNA …
RETRACTED ARTICLE: RNA m6A methylation regulates the epithelial mesenchymal transition of cancer cells and translation of Snail
X Lin, G Chai, Y Wu, J Li, F Chen, J Liu, G Luo… - Nature …, 2019 - nature.com
Abstract N6-Methyladenosine (m6A) modification has been implicated in the progression of
several cancers. We reveal that during epithelial-mesenchymal transition (EMT), one …
several cancers. We reveal that during epithelial-mesenchymal transition (EMT), one …
Critical assessment of DNA adenine methylation in eukaryotes using quantitative deconvolution
The discovery of N6-methyldeoxyadenine (6mA) across eukaryotes led to a search for
additional epigenetic mechanisms. However, some studies have highlighted confounding …
additional epigenetic mechanisms. However, some studies have highlighted confounding …
Regulation of transposable elements by DNA modifications
Maintenance of genome stability requires control over the expression of transposable
elements (TEs), whose activity can have substantial deleterious effects on the host …
elements (TEs), whose activity can have substantial deleterious effects on the host …
Detection of DNA base modifications by deep recurrent neural network on Oxford Nanopore sequencing data
DNA base modifications, such as C5-methylcytosine (5mC) and N6-methyldeoxyadenosine
(6mA), are important types of epigenetic regulations. Short-read bisulfite sequencing and …
(6mA), are important types of epigenetic regulations. Short-read bisulfite sequencing and …
Means, mechanisms and consequences of adenine methylation in DNA
K Boulias, EL Greer - Nature Reviews Genetics, 2022 - nature.com
Abstract N 6-methyl-2′-deoxyadenosine (6mA or m6dA) has been reported in the DNA of
prokaryotes and eukaryotes ranging from unicellular protozoa and algae to multicellular …
prokaryotes and eukaryotes ranging from unicellular protozoa and algae to multicellular …
Prediction of protein–ligand binding affinity from sequencing data with interpretable machine learning
Protein–ligand interactions are increasingly profiled at high throughput using affinity
selection and massively parallel sequencing. However, these assays do not provide the …
selection and massively parallel sequencing. However, these assays do not provide the …
[PDF][PDF] N6-deoxyadenosine methylation in mammalian mitochondrial DNA
Summary N 6-Methyldeoxyadenosine (6mA) has recently been shown to exist and play
regulatory roles in eukaryotic genomic DNA (gDNA). However, the biological functions of …
regulatory roles in eukaryotic genomic DNA (gDNA). However, the biological functions of …
[PDF][PDF] N6-methyladenine DNA modification in the human genome
Summary DNA N 6-methyladenine (6mA) modification is the most prevalent DNA
modification in prokaryotes, but whether it exists in human cells and whether it plays a role in …
modification in prokaryotes, but whether it exists in human cells and whether it plays a role in …