Recent advances of α-glucosidase inhibitors: A comprehensive review
Background: Diabetes mellitus (DM) is a critical health issue prevailing in nearly half a
billion people worldwide. It is one of the most threatening metabolic diseases. Type 2 DM is …
billion people worldwide. It is one of the most threatening metabolic diseases. Type 2 DM is …
Inhibitory effect of flavonoid glycosides on digestive enzymes: In silico, in vitro, and in vivo studies
Flavonoid glycosides (FGs) appear to be good candidates for controlling blood glucose
levels, so regular consumption of vegetables/fruits rich in FGs may prevent the …
levels, so regular consumption of vegetables/fruits rich in FGs may prevent the …
Control of eriocitrin release from pH-sensitive gelatin-based microgels to inhibit α-glucosidase: an experimental and computational study
α-Glucosidase is among the intestinal epithelial enzymes that produce absorbable glucose
in the final stage of glycan catabolism. It leads to an increase in blood glucose levels as a …
in the final stage of glycan catabolism. It leads to an increase in blood glucose levels as a …
((E)‐N′(3,5‐di‐tert‐butil‐2‐hedroxybenzilidene)‐2‐hydroxybenzohydrazide (H3sahz)2 Copper (II) Complex: Synthesis, Crystal Structures, in silico Evaluations, and …
PA Fatullayeva, AA Mejidov, MG Safronenko… - …, 2023 - Wiley Online Library
Abstract In this study,(E)‐N′(3, 5‐di‐tert‐butil‐2‐hedroxybenzilidene)‐2‐
hydroxybenzohydrazide (H3sahz) 2 and its copper (II) complex has been synthesized and …
hydroxybenzohydrazide (H3sahz) 2 and its copper (II) complex has been synthesized and …
Effect of purity of tea polysaccharides on its antioxidant and hypoglycemic activities
M Fan, J Zhu, Y Qian, W Yue, Y Xu… - Journal of Food …, 2020 - Wiley Online Library
The effects of purity of tea polysaccharides (TPS) on its five antioxidant activities and
hypoglycemic activities in vitro were studied. The results showed that the higher the purity of …
hypoglycemic activities in vitro were studied. The results showed that the higher the purity of …
Antioxidant evaluation and computational prediction of prospective drug-like compounds from polyphenolic-rich extract of Hibiscus cannabinus L. seed as …
Background Reports have implicated diabetes mellitus (DM) and Alzheimer's disease (AD)
as some of the global persistent health challenges with no lasting solutions, despite of …
as some of the global persistent health challenges with no lasting solutions, despite of …
Design, synthesis and α-glucosidase inhibition study of novel embelin derivatives
X Chen, M Gao, R Jian, WD Hong, X Tang… - Journal of Enzyme …, 2020 - Taylor & Francis
Embelin is a naturally occurring para-benzoquinone isolated from Embelia ribes (Burm. f.) of
the Myrsinaceae family. It was first discovered to have potent inhibitory activity (IC50= 4.2 …
the Myrsinaceae family. It was first discovered to have potent inhibitory activity (IC50= 4.2 …
Inhibition mechanism of α-glucosidase inhibitors screened from Artemisia selengensis Turcz root
S Wang, X Xie, L Zhang, Y Hu, H Wang, Z Tu - Industrial Crops and …, 2020 - Elsevier
Artemisia selengensis Turcz root (ASTR) is a potential material for screening natural α-
glucosidase inhibitors, which effectively reduce postprandial blood glucose level. In this …
glucosidase inhibitors, which effectively reduce postprandial blood glucose level. In this …
Inhibitory potential of 4-hexylresorcinol against α-glucosidase and non-enzymatic glycation: Activity and mechanism
S Song, Q Liu, WM Chai, SS Xia, ZY Yu… - Journal of bioscience and …, 2021 - Elsevier
Highlights•4-Hexylresorcinol was an efficient inhibitor of α-glucosidase as well as non-
enzymatic glycation.•4-Hexylresorcinol strongly inhibited the formation of advanced …
enzymatic glycation.•4-Hexylresorcinol strongly inhibited the formation of advanced …
The antihyperglycemic potential of pyrazolobenzothiazine 1, 1-dioxide novel derivative in mice using integrated molecular pharmacological approach
Diabetes Mellitus is a metabolic disease characterized by elevated blood sugar levels
caused by inadequate insulin production, which subsequently leads to hyperglycemia. This …
caused by inadequate insulin production, which subsequently leads to hyperglycemia. This …