Traumatic and nontraumatic spinal cord injury: pathological insights from neuroimaging
Pathophysiological changes in the spinal cord white and grey matter resulting from injury
can be observed with MRI techniques. These techniques provide sensitive markers of …
can be observed with MRI techniques. These techniques provide sensitive markers of …
The current state-of-the-art of spinal cord imaging: applications
A first-ever spinal cord imaging meeting was sponsored by the International Spinal
Research Trust and the Wings for Life Foundation with the aim of identifying the current state …
Research Trust and the Wings for Life Foundation with the aim of identifying the current state …
Disability, atrophy and cortical reorganization following spinal cord injury
The impact of traumatic spinal cord injury on structural integrity, cortical reorganization and
ensuing disability is variable and may depend on a dynamic interaction between the severity …
ensuing disability is variable and may depend on a dynamic interaction between the severity …
Demyelination and degeneration in the injured human spinal cord detected with diffusion and magnetization transfer MRI
Characterizing demyelination/degeneration of spinal pathways in traumatic spinal cord
injured (SCI) patients is crucial for assessing the prognosis of functional rehabilitation. Novel …
injured (SCI) patients is crucial for assessing the prognosis of functional rehabilitation. Novel …
Functional brain reorganization after spinal cord injury: systematic review of animal and human studies
Plastic changes of neural circuits occur after spinal cord injury (SCI) at various level of the
central nervous system. In this review we will focus on delineating the pathophysiological …
central nervous system. In this review we will focus on delineating the pathophysiological …
Progressive neurodegeneration following spinal cord injury: implications for clinical trials
G Ziegler, P Grabher, A Thompson, D Altmann… - Neurology, 2018 - AAN Enterprises
Objective To quantify atrophy, demyelination, and iron accumulation over 2 years following
acute spinal cord injury and to identify MRI predictors of clinical outcomes and determine …
acute spinal cord injury and to identify MRI predictors of clinical outcomes and determine …
Spinal cord imaging in amyotrophic lateral sclerosis: historical concepts—novel techniques
MM El Mendili, G Querin, P Bede, PF Pradat - Frontiers in neurology, 2019 - frontiersin.org
Amyotrophic lateral sclerosis (ALS) is the most common adult onset motor neuron disease
with no effective disease modifying therapies at present. Spinal cord degeneration is a …
with no effective disease modifying therapies at present. Spinal cord degeneration is a …
Tracking sensory system atrophy and outcome prediction in spinal cord injury
P Grabher, MF Callaghan, J Ashburner… - Annals of …, 2015 - Wiley Online Library
Objective In patients with subacute spinal cord injury (SCI), the motor system undergoes
progressive structural changes rostral to the lesion, which are associated with motor …
progressive structural changes rostral to the lesion, which are associated with motor …
Association of pain and CNS structural changes after spinal cord injury
Traumatic spinal cord injury (SCI) has been shown to trigger structural atrophic changes
within the spinal cord and brain. However, the relationship between structural changes and …
within the spinal cord and brain. However, the relationship between structural changes and …
Involvement of spinal sensory pathway in ALS and specificity of cord atrophy to lower motor neuron degeneration
J Cohen-Adad, MME Mendili… - … Lateral Sclerosis and …, 2013 - Taylor & Francis
Our objective was to demonstrate that ALS patients have sensory pathway involvement and
that local cord atrophy reflects segmental lower motor neuron involvement. Twenty-nine ALS …
that local cord atrophy reflects segmental lower motor neuron involvement. Twenty-nine ALS …