The life sciences are currently being transformed by an unprecedented wave of
developments in molecular analysis, which include important advances in instrumental …

Metabolomics provides a comprehensive assessment of numerous small molecules in
biological samples. As it integrates the effects of exogenous exposures, endogenous …

Mass spectrometry (MS) techniques, because of their sensitivity and selectivity, have
become methods of choice to characterize the human metabolome and MS-based …

Metabolomics can be significantly influenced by a range of pre-analytical factors, such as
sample collection, pre-processing, aliquoting, transport, storage and thawing. This therefore …

BACKGROUND Metabolomics is a powerful tool that is increasingly used in clinical
research. Although excellent sample quality is essential, it can easily be compromised by …

BACKGROUND Rigorous studies are necessary to demonstrate suitability of metabolomics
platforms to profile metabolites in archived plasma within epidemiologic studies of human …

Stress plays an important role in psychiatric disorders, and preclinical evidence indicates
that the central endocannabinoid system modulates endocrine and neuronal responses to …

Notwithstanding the ongoing debate on their full potential in health and disease, there is
general consensus that n-3 PUFAs play important physiological roles. Increasing dietary n-3 …

The analysis of metabolites in human body fluids remains a challenge because of their
chemical diversity and dynamic concentration range. Liquid chromatography (LC) in …

Metabolomics is one of the most recently emerged “-omics” sciences. Its significance in
systems biology is gaining interest to levels similar to proteomics, transcriptomics and …