Diabetic nephropathy is a significant cause of chronic kidney disease and end-stage renal
failure globally. Much research has been conducted in both basic science and clinical …

Diabetic nephropathy is the leading cause of kidney disease in patients starting renal
replacement therapy and affects∼ 40% of type 1 and type 2 diabetic patients. It increases …

Aims/hypothesis Endothelial glycocalyx perturbation contributes to increased vascular
permeability. In the present study we set out to evaluate whether:(1) glycocalyx is perturbed …

Diabetes is a worldwide epidemic that has led to a rise in diabetic kidney disease (DKD).
Over the past two decades, there has been significant clarification of the various pathways …

As CKD continues to increase worldwide, along with the demand for related life-saving
therapies, the financial burden of CKD will place an increasing drain on health care systems …

Proteinuria is the hallmark of diabetic kidney disease (DKD) and is an independent risk
factor for both renal disease progression, and cardiovascular disease. Although the …

Excretion of albumin in the urine is highly variable, ranging from nondetectable quantities to
milligrams of albumin and even grams of albumin. Microalbuminuria is defined as low levels …

To reduce the burden of cardiovascular disease (CVD), management strategies are
increasingly focusing on preventive measures following early detection of markers of …

The classic Starling principle proposed that microvascular fluid exchange was determined
by a balance of hydrostatic and oncotic pressures relative to the vascular wall and this …

Carl Erik Mogensen Medical Department M, Diabetes and Endocrinology, Aarhus
Kommunehospital, Aarhus University Hospital, Aarhus, Denmark (Modified from …