Metal drugs and the anticancer immune response

B Englinger, C Pirker, P Heffeter, A Terenzi… - Chemical …, 2018 - ACS Publications
The immune system deploys a multitude of innate and adaptive mechanisms not only to
ward off pathogens but also to prevent malignant transformation (“immune surveillance”) …

Update on metal N-heterocyclic carbene complexes as potential anti-tumor metallodrugs

W Liu, R Gust - Coordination Chemistry Reviews, 2016 - Elsevier
The clinical success of platinum-based chemotherapeutic agents was of enormous impact
on the discovery of novel metal N-heterocyclic carbene (NHC) complexes as potential anti …

[HTML][HTML] Evaluation of metal-based antimicrobial compounds for the treatment of bacterial pathogens

A Evans, KA Kavanagh - Journal of Medical Microbiology, 2021 - microbiologyresearch.org
Antimicrobial resistance (AMR) is one of the greatest global health challenges of modern
times and its prevalence is rising worldwide. AMR within bacteria reduces the efficacy of …

Silver coordination compounds: A new horizon in medicine

S Medici, M Peana, G Crisponi, VM Nurchi… - Coordination Chemistry …, 2016 - Elsevier
Silver coordination compounds with a number of different ligands (N-heterocyclic carbenes,
phosphines, N-heterocycles and others) possess several properties, ranging from …

[HTML][HTML] Recent studies on the antimicrobial activity of transition metal complexes of groups 6–12

S Nasiri Sovari, F Zobi - Chemistry, 2020 - mdpi.com
Antimicrobial resistance is an increasingly serious threat to global public health that requires
innovative solutions to counteract new resistance mechanisms emerging and spreading …

Click-derived multifunctional metal complexes for diverse applications

MG Ahmad, MM Balamurali, K Chanda - Chemical Society Reviews, 2023 - pubs.rsc.org
The Click reaction that involves Cu (I)-catalyzed azide–alkyne cycloaddition (CuAAC) serves
as the most potent and highly dependable tool for the development of many complex …

[HTML][HTML] Synthesis of ruthenium complexes and their catalytic applications: A review

J Hafeez, M Bilal, N Rasool, U Hafeez… - Arabian Journal of …, 2022 - Elsevier
Ruthenium complexes are an important class that has multiple catalytic and biological
applications. Ruthenium has a remarkably broad and diversified chemical spectrum. In the …

[HTML][HTML] Metal-based compounds containing selenium: An appealing approach towards novel therapeutic drugs with anticancer and antimicrobial effects

S Ramos-Inza, D Plano, C Sanmartín - European Journal of Medicinal …, 2022 - Elsevier
In recent years, both metal-based complexes and selenium-containing compounds have
been widely explored for their therapeutic properties due to their roles in biological …

Metal-based BODIPY derivatives as multimodal tools for life sciences

B Bertrand, K Passador, C Goze, F Denat… - Coordination Chemistry …, 2018 - Elsevier
Abstract Nowadays, 4, 4-difluoro-4-bora-3a, 4a-diaza-s-indacene–better known as BODIPY
radical dot–is at the forefront of fluorophores for life sciences. Indeed, its high brightness, its …

Advances in alkynyl gold complexes for use as potential anticancer agents

Z Yang, G Jiang, Z Xu, S Zhao, W Liu - Coordination Chemistry Reviews, 2020 - Elsevier
Gold-based anticancer agents have gained the widespread attention of medicinal inorganic
chemists due to their unique chemical properties and strong antiproliferative potency …