Context-specific regulation of extracellular vesicle biogenesis and cargo selection
AC Dixson, TR Dawson, D Di Vizio… - … Reviews Molecular Cell …, 2023 - nature.com
To coordinate, adapt and respond to biological signals, cells convey specific messages to
other cells. An important aspect of cell–cell communication involves secretion of molecules …
other cells. An important aspect of cell–cell communication involves secretion of molecules …
Exosomes─ nature's lipid nanoparticles, a rising star in drug delivery and diagnostics
Exosomes are a subgroup of nanosized extracellular vesicles enclosed by a lipid bilayer
membrane and secreted by most eukaryotic cells. They represent a route of intercellular …
membrane and secreted by most eukaryotic cells. They represent a route of intercellular …
Extracellular vesicles and nanoparticles: emerging complexities
The study of extracellular vesicles (EVs) and nanoparticles (NPs) is rapidly expanding
because recent discoveries have revealed a much greater complexity and diversity than was …
because recent discoveries have revealed a much greater complexity and diversity than was …
Liquid biopsy: a step closer to transform diagnosis, prognosis and future of cancer treatments
Over the past decade, invasive techniques for diagnosing and monitoring cancers are slowly
being replaced by non-invasive methods such as liquid biopsy. Liquid biopsies have …
being replaced by non-invasive methods such as liquid biopsy. Liquid biopsies have …
RNA-based therapeutics: an overview and prospectus
Y Zhu, L Zhu, X Wang, H Jin - Cell death & disease, 2022 - nature.com
The growing understanding of RNA functions and their crucial roles in diseases promotes
the application of various RNAs to selectively function on hitherto “undruggable” proteins …
the application of various RNAs to selectively function on hitherto “undruggable” proteins …
Therapeutically harnessing extracellular vesicles
The field of extracellular vesicle (EV) research has developed rapidly over the last decade
from the study of fundamental biology to a subject of significant clinical relevance. The …
from the study of fundamental biology to a subject of significant clinical relevance. The …
MicroRNA sequence codes for small extracellular vesicle release and cellular retention
Exosomes and other small extracellular vesicles (sEVs) provide a unique mode of cell-to-
cell communication in which microRNAs (miRNAs) produced and released from one cell are …
cell communication in which microRNAs (miRNAs) produced and released from one cell are …
Mesenchymal stem cell-derived extracellular vesicles for immunomodulation and regeneration: a next generation therapeutic tool?
M Kou, L Huang, J Yang, Z Chiang, S Chen, J Liu… - Cell Death & …, 2022 - nature.com
Mesenchymal stem cells (MSCs) can be widely isolated from various tissues including bone
marrow, umbilical cord, and adipose tissue, with the potential for self-renewal and …
marrow, umbilical cord, and adipose tissue, with the potential for self-renewal and …
MicroRNA-based diagnosis and therapy
MicroRNAs (miRNAs) are a group of endogenous non-coding RNAs that regulate gene
expression. Alteration in miRNA expression results in changes in the profile of genes …
expression. Alteration in miRNA expression results in changes in the profile of genes …
Review on strategies and technologies for exosome isolation and purification
J Chen, P Li, T Zhang, Z Xu, X Huang… - … in bioengineering and …, 2022 - frontiersin.org
Exosomes, a nano-sized subtype of extracellular vesicles secreted from almost all living
cells, are capable of transferring cell-specific constituents of the source cell to the recipient …
cells, are capable of transferring cell-specific constituents of the source cell to the recipient …