Nanoparticle drug delivery systems and their applications as targeted therapies for triple negative breast cancer
The therapeutic effect of highly malignant triple negative breast cancer (TNBC) is negatively
affected by the formation of tumor cell resistant clone and the severe toxicity of …
affected by the formation of tumor cell resistant clone and the severe toxicity of …
The role of glutamate receptors in the regulation of the tumor microenvironment
S Koda, J Hu, X Ju, G Sun, S Shao, RX Tang… - Frontiers in …, 2023 - frontiersin.org
Glutamate, as one of the most important carbon sources in the TCA cycle, is central in
metabolic processes that will subsequently influence tumor progression. Several factors can …
metabolic processes that will subsequently influence tumor progression. Several factors can …
Brain‐targeted liposomes loaded with monoclonal antibodies reduce alpha‐synuclein aggregation and improve behavioral symptoms in Parkinson's disease
Monoclonal antibodies (mAbs) hold promise in treating Parkinson's disease (PD), although
poor delivery to the brain hinders their therapeutic application. In the current study, it is …
poor delivery to the brain hinders their therapeutic application. In the current study, it is …
Beta-blockade enhances anthracycline control of metastasis in triple-negative breast cancer
Beta-adrenergic blockade has been associated with improved cancer survival in patients
with triple-negative breast cancer (TNBC), but the mechanisms of these effects remain …
with triple-negative breast cancer (TNBC), but the mechanisms of these effects remain …
NMDAR antagonists suppress tumor progression by regulating tumor-associated macrophages
D Yuan, J Hu, X Ju, EM Putz, S Zheng… - Proceedings of the …, 2023 - National Acad Sciences
Neurotransmitter receptors are increasingly recognized to play important roles in anti-tumor
immunity. The expression of the ion channel N-methyl-D-aspartate receptor (NMDAR) on …
immunity. The expression of the ion channel N-methyl-D-aspartate receptor (NMDAR) on …
Perineural invasion in pancreatic ductal adenocarcinoma: from molecules towards drugs of clinical relevance
F Selvaggi, E Melchiorre, I Casari, S Cinalli, M Cinalli… - Cancers, 2022 - mdpi.com
Simple Summary A few types of cancers are currently as challenging and difficult to defeat
as pancreatic ductal adenocarcinoma. Several reasons contribute to the complexity of this …
as pancreatic ductal adenocarcinoma. Several reasons contribute to the complexity of this …
Recent progress in nanocarrier-based drug delivery systems for antitumour metastasis
S Peng, X Yuan, H Li, Y Wei, B Zhou, G Ding… - European Journal of …, 2023 - Elsevier
Tumour metastasis is one of the major factors leading to poor prognosis as well as lower
survival among cancer patients. A number of studies investigating the inhibition of tumour …
survival among cancer patients. A number of studies investigating the inhibition of tumour …
[HTML][HTML] Genomic instability drives tumorigenesis and metastasis and its implications for cancer therapy
S Guo, X Zhu, Z Huang, C Wei, J Yu, L Zhang… - Biomedicine & …, 2023 - Elsevier
Genetic instability can be caused by external factors and may also be associated with
intracellular damage. At the same time, there is a large body of research investigating the …
intracellular damage. At the same time, there is a large body of research investigating the …
Fluorescent multifunctional organic nanoparticles for drug delivery and bioimaging: a tutorial review
Fluorescent organic nanoparticles (FONs) are a large family of nanostructures constituted by
organic components that emit light in different spectral regions upon excitation, due to the …
organic components that emit light in different spectral regions upon excitation, due to the …
Targeted intervention in nerve–cancer crosstalk enhances pancreatic cancer chemotherapy
J Qin, J Liu, Z Wei, X Li, Z Chen, J Li, W Zheng… - Nature …, 2024 - nature.com
Nerve–cancer crosstalk has gained substantial attention owing to its impact on tumour
growth, metastasis and therapy resistance. Effective therapeutic strategies targeting tumour …
growth, metastasis and therapy resistance. Effective therapeutic strategies targeting tumour …